THE TREATMENT OF DISSEMINATED PROSTATE-CANCER WITH ESTRAMUSTINE

被引：1
|
作者：
ROSENTHAL, MA [1 ]
RAGHAVAN, D [1 ]
STUARTHARRIS, R [1 ]
ACKLAND, S [1 ]
GRYGIEL, J [1 ]
机构：
[1] ROYAL PRINCE ALFRED HOSP,UROL CANC RES UNIT,LEVEL E9,CAMPERDOWN,NSW 2050,AUSTRALIA
来源：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF SURGERY | 1992年 / 62卷 / 11期
关键词：
ESTRAMUSTINE; PROSTATE CANCER;
D O I：
10.1111/j.1445-2197.1992.tb06942.x
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
Forty-three patients with disseminated prostate cancer, resistant to orchidectomy or hormone therapy with estramustine were treated. Of the 33 evaluable patients, three patients had stable disease and two had a partial tumour response according to National Prostatic Cancer Project criteria. Twenty-five patients (58%) showed improvement in pain and urinary symptoms. Ten patients (23%) had side effects requiring cessation of therapy. These results show that estramustine has a limited role in the treatment of advanced prostate cancer and that therapy is frequently associated with intolerable side effects.
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页码：871 / 873
页数：3
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