MUTATIONS IN THE PRECURSOR REGION OF A BACILLUS-SUBTILIS SPORULATION SIGMA FACTOR

被引:7
|
作者
RONG, S [1 ]
SONENSHEIN, AL [1 ]
机构
[1] TUFTS UNIV,DEPT MOLEC BIOL & MICROBIOL,HLTH SCI CAMPUS,136 HARRISON AVE,BOSTON,MA 02111
关键词
D O I
10.1128/JB.174.11.3812-3817.1992
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Transcription from some sporulation-specific promoters of Bacillus subtilis is dependent on synthesis of pro-sigma(E) and its conversion to sigma(E) by proteolysis. Certain mutations in the precursor region of sigE, the gene encoding pro-sigma(E), apparently allow the mutant sigE products to be active as sigma-factors without being proteolysed in the normal way.
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页码:3812 / 3817
页数:6
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