EFFECT OF RESERPINE ON RETENTION OF THE CONDITIONED NK CELL RESPONSE

被引：12
|
作者：
HIRAMOTO, R
SOLVASON, B
GHANTA, V
LORDEN, J
HIRAMOTO, N
机构：
[1] UNIV ALABAMA, DEPT BIOL, BIRMINGHAM, AL 35294 USA
[2] UNIV ALABAMA, DEPT PSYCHOL, NEUROPSYCHIAT RES PROGRAM, BIRMINGHAM, AL 35294 USA
[3] UNIV ALABAMA, CTR COMPREHENS CANC, BIRMINGHAM, AL 35294 USA
[4] VET ADM MED CTR, BIRMINGHAM, AL 35294 USA
来源：
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1990年 / 36卷 / 01期
关键词：
6-Hydroxydopamine; Camphor odor; Conditioned response; Reserpine;
D O I：
10.1016/0091-3057(90)90124-Z
中图分类号：
B84 [心理学]; C [社会科学总论]; Q98 [人类学];
学科分类号：
03 ; 0303 ; 030303 ; 04 ; 0402 ;
摘要：
The effect of reserpine and 6-hydroxydopamine on the learned conditioned natural killer (NK) cell response was investigated in mice. Reserpine given at 2.5 mg/kg, 24 hr prior to reexposure to camphor-conditioned stimulus on days 6 and 8 blocked the recall of conditioned NK cell response to a significant extent. In other words, the NK cell activity of conditioned mice, treated with reserpine and reexposed to the conditioned stimulus, was similar to the nonconditioned (NC) group. A conditioned increase in NK cell response was still evident in mice treated with 6-OHDA. © 1990.
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页码：51 / 56
页数：6
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