Polytolypin, a new antifungal triterpenoid from the coprophilous fungus Polytolypa hystricis

被引:14
|
作者
Gamble, WR
Gloer, JB
Scott, JA
Malloch, D
机构
[1] UNIV IOWA,DEPT CHEM,IOWA CITY,IA 52242
[2] UNIV TORONTO,DEPT BOT,TORONTO,ON M5S 1A1,CANADA
来源
JOURNAL OF NATURAL PRODUCTS | 1995年 / 58卷 / 12期
关键词
D O I
10.1021/np50126a034
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Polytolypin [1], a new pentacyclic triterpenoid exhibiting antifungal and antibiotic activity, has been isolated from cultures of Polytolypa hystricis (JS189), a fungal colonist of porcupine dung. Two known compounds [2 and 3] were also isolated. Polytolypin was obtained by chromatographic fractionation of the EtOAc extract of P. hystricis liquid cultures, and the structure was assigned on the basis of 2D nmr and hrms data.
引用
收藏
页码:1983 / 1986
页数:4
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