Comparative effect of fixed dose combination of Amlodipine

被引：0
|
作者：
Shirure, P. A. [1 ]
Tadvi, N. A. [2 ]
Bajait, C. S. [3 ]
Baig, M. S. [4 ]
Gade, P. R. [5 ]
机构：
[1] GMC, Dept Pharmacol, Nanded, Maharashtra, India
[2] KIMS, Dept Pharmacol, Narketpally, Andhra Pradesh, India
[3] GMC, Dept Pharmacol, Nagpur, Maharashtra, India
[4] GMC, Dept Pharmacol, Aurangabad, Maharashtra, India
[5] MIMSR Med Coll, Dept Pharmacol, Latur, Maharashtra, India
来源：
INTERNATIONAL JOURNAL OF MEDICAL RESEARCH & HEALTH SCIENCES | 2012年 / 1卷 / 01期
关键词：
Amlodipine; Bisoprolol; Hypertension stage-2;
D O I：
暂无
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Background: Employment of low dose combinations of two antihypertensives, with different mode of action has gained acceptance worldwide for the treatment of mild to moderate hypertension. However, most studies in hypertensive disease have focused on monotherapy. The combination therapy in the treatment of hypertension is largely extrapolated from these monotherapy studies. Objectives: To study and compare the effect of amlodipine, bisoprolol and fixed dose combination of amlodipine + bisoprolol on blood pressure in stage-2 essential hypertensive patients. Methods: The present study was carried out in Department of Pharmacology in collaboration with Department of Medicine at Government Medical College and Hospital, Aurangabad. Results and Conclusion : Amlodipine + bisoprolol in fixed dose combination have showed significant blood pressure control in patients of stage- 2 essential hypertension and the antihypertensive effect was greater than individual monotherapy study groups.
引用
收藏
页码：13 / 19
页数：7
相关论文
共 50 条
  • [41] The effect of fixed-dose combination of valsartan and amlodipine on nighttime blood pressure in patients with non-dipper hypertension
    Erdogan, Dogan
    Icli, Atilla
    Aksoy, Fatih
    Akcay, Salaheddin
    Yucel, Habil
    Ersoy, Ibrahim
    Ozaydin, Mehmet
    TURK KARDIYOLOJI DERNEGI ARSIVI-ARCHIVES OF THE TURKISH SOCIETY OF CARDIOLOGY, 2016, 44 (05): : 404 - 413
  • [42] Pharmacoeconomic Efficacy of a Fixed Combination of Bisoprolol and Amlodipine
    Tarlovskaya, E. I.
    Skibitskiy, V. V.
    Malchikova, S. V.
    Fendrikova, A. V.
    Skibitskiy, A. V.
    Sirotenko, D. V.
    KARDIOLOGIYA, 2015, 55 (04) : 25 - 29
  • [43] Persistence on treatment with the fixed combination of ramipril and amlodipine
    Simonyi Gabor
    Ferenci Tamas
    ORVOSI HETILAP, 2014, 155 (47) : 1882 - 1888
  • [44] Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin with Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers
    Yoon, Deok Yong
    Park, Sang-In
    Jung, Jin-A
    Kim, Yong-Il
    Jang, In-Jin
    Chung, Jae-Yong
    DRUG DESIGN DEVELOPMENT AND THERAPY, 2020, 14 : 661 - 668
  • [45] Pharmacokinetics of Amlodipine and Olmesartan After Administration of Amlodipine Besylate and Olmesartan Medoxomil in Separate Dosage Forms and as a Fixed-Dose Combination
    Rohatagi, Shashank
    Lee, James
    Shenouda, Magdy
    Haworth, Stephen
    Bathala, Mohinder Singh
    Allison, Mark
    Rubets, Igor
    Heyrman, Reinilde
    Noveck, Robert
    Salazar, Daniel E.
    JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 48 (11): : 1309 - 1322
  • [46] An Expert Opinion on the Role of the Rosuvastatin/Amlodipine Single Pill Fixed Dose Combination in Cardiovascular Prevention
    Giovanna Gallo
    Riccardo Sarzani
    Arrigo Francesco Giuseppe Cicero
    Stefano Genovese
    Matteo Pirro
    Luca Gallelli
    Andrea Faggiano
    Massimo Volpe
    High Blood Pressure & Cardiovascular Prevention, 2023, 30 : 83 - 91
  • [47] Fixed-dose combination of perindopril and amlodipine for the management of hypertension with or without coronary artery disease
    Ferrari, Roberto
    Ceconi, Claudio
    REVISTA DE LA FEDERACION ARGENTINA DE CARDIOLOGIA, 2011, 40 (04): : 323 - 334
  • [48] SAFETY AND EFFICACY OF INDAPAMIDE SUSTAINED RELEASE/AMLODIPINE FIXED-DOSE COMBINATION IN ESSENTIAL HYPERTENSION
    Bricout-Hennel, S.
    Zelveian, P.
    Nedogoda, S.
    JOURNAL OF HYPERTENSION, 2018, 36 : E45 - E45
  • [49] Comparative effect of fixed-dose combination tablets of candesartan cilexetil/amlodipine versus olmesartan medoxomil/azelnidipine on laboratory parameters in patients with hypertension: a retrospective cohort study
    Susa, Norio
    Nishida, Yayoi
    Yada, Yoichi
    Nakayama, Tomohiro
    Asai, Satoshi
    Takahashi, Yasuo
    CLINICAL AND EXPERIMENTAL HYPERTENSION, 2016, 38 (02) : 173 - 179
  • [50] Does a fixed-dose combination of amlodipine and atorvastatin improve persistence with therapy in the Australian population?
    Bartlett, Louise E.
    Pratt, Nicole
    Roughead, Elizabeth E.
    CURRENT MEDICAL RESEARCH AND OPINION, 2018, 34 (02) : 305 - 311
12345