Comparative effect of fixed dose combination of Amlodipine

被引：0

作者：

Shirure, P. A. ^{[1
]}

Tadvi, N. A. ^{[2
]}

Bajait, C. S. ^{[3
]}

Baig, M. S. ^{[4
]}

Gade, P. R. ^{[5
]}

机构：

[1] GMC, Dept Pharmacol, Nanded, Maharashtra, India

[2] KIMS, Dept Pharmacol, Narketpally, Andhra Pradesh, India

[3] GMC, Dept Pharmacol, Nagpur, Maharashtra, India

[4] GMC, Dept Pharmacol, Aurangabad, Maharashtra, India

[5] MIMSR Med Coll, Dept Pharmacol, Latur, Maharashtra, India

来源：

INTERNATIONAL JOURNAL OF MEDICAL RESEARCH & HEALTH SCIENCES | 2012年 / 1卷 / 01期

关键词：

Amlodipine; Bisoprolol; Hypertension stage-2;

D O I：

暂无

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Background: Employment of low dose combinations of two antihypertensives, with different mode of action has gained acceptance worldwide for the treatment of mild to moderate hypertension. However, most studies in hypertensive disease have focused on monotherapy. The combination therapy in the treatment of hypertension is largely extrapolated from these monotherapy studies. Objectives: To study and compare the effect of amlodipine, bisoprolol and fixed dose combination of amlodipine + bisoprolol on blood pressure in stage-2 essential hypertensive patients. Methods: The present study was carried out in Department of Pharmacology in collaboration with Department of Medicine at Government Medical College and Hospital, Aurangabad. Results and Conclusion : Amlodipine + bisoprolol in fixed dose combination have showed significant blood pressure control in patients of stage- 2 essential hypertension and the antihypertensive effect was greater than individual monotherapy study groups.

引用

页码：13 / 19

页数：7

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