CLONING AND SEQUENCE-ANALYSIS OF A MURINE CDNA-ENCODING GLUTAMATE-DECARBOXYLASE (GAD65)

被引：36
|
作者：
LEE, DS [1 ]
TIAN, JD [1 ]
PHAN, T [1 ]
KAUFMAN, DL [1 ]
机构：
[1] UNIV CALIF LOS ANGELES,SCH MED,DEPT PSYCHIAT & BIOBEHAV SCI,760 WESTWOOD PLAZA,LOS ANGELES,CA 90024
来源：
BIOCHIMICA ET BIOPHYSICA ACTA | 1993年 / 1216卷 / 01期
关键词：
GLUTAMATE DECARBOXYLASE; CDNA; CLONING; GAD; GABA; DIABETES; (NOD MOUSE);
D O I：
10.1016/0167-4781(93)90056-J
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
We report the cloning and cDNA sequence of murine GAD65. Murine GAD65 is comprised of 585 amino acids and shares a high degree of homology with human and rat GAD65, with most divergences occurring near their amino-termini. The murine GAD65 sequence will allow evaluation of the role of this gene in murine neurogenetic and autoimmune diseases.
引用
收藏
页码：157 / 160
页数：4
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