PNEUMOLYSIN STIMULATES PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA AND INTERLEUKIN-1-BETA BY HUMAN MONONUCLEAR PHAGOCYTES

被引：149

作者：

HOULDSWORTH, S ^{[1
]}

ANDREW, PW ^{[1
]}

MITCHELL, TJ ^{[1
]}

机构：

[1] UNIV LEICESTER,DEPT MICROBIOL & IMMUNOL,LEICESTER LE1 9HN,ENGLAND

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 04期

关键词：

D O I：

10.1128/IAI.62.4.1501-1503.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human peripheral blood monocytes and a human monocyte cell line were exposed to the toxin pneumolysin. Pneumolysin-exposed cells produced significantly larger amounts of tumor necrosis factor alpha and interleukin-1 beta than cells not exposed to the toxin. The viability of cells was not affected by the concentrations of pneumolysin used in the experiments.

引用

页码：1501 / 1503

页数：3

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