HUMAN HERPESVIRUS-6 IN SALIVARY-GLANDS

被引：156
|
作者：
FOX, JD
BRIGGS, M
WARD, PA
TEDDER, RS
机构：
[1] Department of Medical Microbiology, University College, Middlesex School of Medicine, London, W1 P 7PN
来源：
LANCET | 1990年 / 336卷 / 8715期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/0140-6736(90)93392-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
In an investigation of the role of saliva in the transmission of human herpesvirus 6 (HHV6) sections of salivary gland tissue were screened for HHV6-specific DNA by in-situ hybridisation and for HHV6-specific protein by immunohistochemical staining with monoclonal antibodies against the virus. All of nine submandibular glands and one of four parotid glands showed the presence of H HV6 genome and expressed protein by these techniques. The findings are consistent with transmission of HHV6 by saliva and suggest that salivary gland tissue is a site of replication of the virus and a potential site for HHV6 persistence. © 1990.
引用
收藏
页码：590 / 593
页数：4
相关论文
共 50 条
  • [41] THE QUANTITATIVE HISTOLOGY OF THE HUMAN LINGUAL SALIVARY-GLANDS
    DRUMMOND, JR
    JOURNAL OF DENTAL RESEARCH, 1989, 68 (04) : 629 - 629
  • [42] EXPRESSION OF INTERMEDIATE FILAMENTS IN HUMAN SALIVARY-GLANDS
    GEIGER, SB
    MARSHAK, G
    LEITNERGIGI, O
    GEIGER, B
    JOURNAL OF DENTAL RESEARCH, 1986, 65 (04) : 574 - 574
  • [43] THE DISTRIBUTION OF GLYCOCONJUGATES IN NORMAL HUMAN SALIVARY-GLANDS
    MCMAHON, RFT
    BENBOW, EW
    LOFTHOUSE, AK
    STODDART, RW
    JOURNAL OF PATHOLOGY, 1988, 155 (04): : A350 - A350
  • [44] PRENATAL DEVELOPMENT OF HUMAN MINOR SALIVARY-GLANDS
    SAMAR, ME
    DEFERRARIS, MEG
    AVILA, RE
    FERRARIS, R
    DEFABRO, SP
    JOURNAL OF DENTAL RESEARCH, 1989, 68 (04) : 536 - 536
  • [45] ANTIBODY TO HUMAN HERPESVIRUS-6 IN SALIVA
    PIETROBONI, GR
    HARNETT, GB
    BUCENS, MR
    HONESS, RW
    LANCET, 1988, 1 (8593): : 1059 - 1059
  • [46] PATHOGENICITY OF HUMAN HERPESVIRUS-6 - REPLY
    ASANO, Y
    YOSHIKAWA, T
    SUGA, S
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1991, 10 (12) : 957 - 958
  • [47] HUMAN HERPESVIRUS-6 INFECTION AND DISEASE
    KRUEGER, GRF
    LANCET, 1988, 2 (8609): : 518 - 518
  • [48] HUMAN HERPESVIRUS-6 MENINGOENCEPHALITIS WITH SEQUELAE
    YANAGIHARA, K
    TANAKATAYA, K
    ITAGAKI, Y
    TORIBE, Y
    ARITA, K
    YAMANISHI, K
    OKADA, S
    PEDIATRIC INFECTIOUS DISEASE JOURNAL, 1995, 14 (03) : 240 - 242
  • [49] HUMAN HERPESVIRUS-6 AND EXANTHEM SUBITUM
    TAKAHASHI, K
    SONODA, S
    KAWAKAMI, K
    MIYATA, K
    OKI, T
    NAGATA, T
    OKUNO, T
    YAMANISHI, K
    LANCET, 1988, 1 (8600): : 1463 - 1463
  • [50] MENINGITIS CAUSED BY HUMAN HERPESVIRUS-6
    HUANG, LM
    LEE, CY
    LEE, PI
    CHEN, JM
    WANG, PJ
    ARCHIVES OF DISEASE IN CHILDHOOD, 1991, 66 (12) : 1443 - 1444
12345