INFLUENCE OF BEZAFIBRATE AND COLESTIPOL ON LDL-CHOLESTEROL, LDL-APOLIPOPROTEIN-B AND HDL-CHOLESTEROL IN HYPERLIPOPROTEINEMIA

被引：0
|
作者：
KLOSIEWICZLATOSZEK, L
NOWICKA, G
SZOSTAK, WB
NARUSZEWICZ, M
机构：
来源：
ATHEROSCLEROSIS | 1987年 / 63卷 / 2-3期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A significant increase of LDL-apolipoprotein B by 13% and LDL-cholesterol by 19% was observed in a group of 9 patients with hyperlipoproteinaemia Type III after bezafibrate treatment. Additional administration of colestipol caused a significant decrease of both LDL-apolipoprotein B by 18% and LDL-cholesterol by 25%. In 10 patients of hyperlipoproteinaemia Type IIb a significant decrease of both LDL-apolipoprotein B by 28% and LDL-apolipoprotein B by 18% was observed after bezafibrate therapy. When bezafibrate was given together with colestipol a further decrease of both LDL-cholesterol by 17% and LDL-apolipoprotein B by 16% occurred. HDL-cholesterol concentration increased significantly in both groups of hyperlipaemic patients during therapy. This may be the effect of both bezafibrate and colestipol. It is concluded that bile acid resins may effectively prevent the LDL-cholesterol concentration increase observed sometimes after clofibrate analogues.
引用
收藏
页码：203 / 209
页数：7
相关论文
共 50 条
  • [41] Viscous soluble fiber combined with phytosterols and policosanol reduces LDL-cholesterol and increases HDL-cholesterol in hypercholesterolemia
    Verdegem, Peter J. E.
    CURRENT TOPICS IN NUTRACEUTICAL RESEARCH, 2007, 5 (01) : 1 - 6
  • [42] ANALYSIS OF HDL-CHOLESTEROL AND (VLDL + LDL) - CHOLESTEROL IN HEPATIC AND INTESTINAL DISORDERS
    REMYHEINTZ, N
    CASSANAS, G
    ANDORRA, M
    ANNALES DE BIOLOGIE CLINIQUE, 1990, 48 (04) : 259 - 262
  • [43] ACTION OF PIROZADIL (PEMIX) ON CHOLESTEROL, LDL-CHOLESTEROL AND APOLIPOPROTEIN-A AND APOLIPOPROTEIN-B IN HYPERLIPEMIC PATIENTS
    COROMINAS, A
    CLINICAL TRIALS JOURNAL, 1985, 22 (01) : 84 - 93
  • [44] Reference ranges for serum total cholesterol, HDL-cholesterol, LDL-cholesterol, and VLDL-cholesterol and triglycerides in healthy iranian ahvaz population
    Jalali M.T.
    Honomaror A.M.
    Rekabi A.
    Latifi M.
    Indian Journal of Clinical Biochemistry, 2013, 28 (3) : 277 - 282
  • [45] THE EFFECT OF TRIPHASIC AND BIPHASIC ORAL-CONTRACEPTIVE PREPARATIONS ON HDL-CHOLESTEROL AND LDL-CHOLESTEROL IN YOUNG-WOMEN
    PERCIVALSMITH, RKL
    MORRISON, BJ
    SIZTO, R
    ABERCROMBIE, B
    CONTRACEPTION, 1987, 35 (02) : 179 - 187
  • [46] INCREASES IN HDL-CHOLESTEROL AND THE HDL/LDL CHOLESTEROL RATIO DURING PROLONGED ENDURANCE EXERCISE
    DURSTINE, JL
    MILLER, W
    FARRELL, S
    SHERMAN, WM
    IVY, JL
    METABOLISM-CLINICAL AND EXPERIMENTAL, 1983, 32 (10): : 993 - 997
  • [47] LDL-cholesterol/apolipoprotein B ratio is a good predictor of LDL phenotype B in type 2 diabetes
    Wägner, AM
    Jorba, O
    Rigla, M
    Alonso, E
    Ordóñez-Llanos, J
    Pérez, A
    ACTA DIABETOLOGICA, 2002, 39 (04) : 215 - 220
  • [48] LDL-cholesterol/apolipoprotein B ratio is a good predictor of LDL phenotype B in type 2 diabetes
    A.M. Wägner
    O. Jorba
    M. Rigla
    E. Alonso
    J. Ordóñez-Llanos
    A. Pérez
    Acta Diabetologica, 2002, 39 : 215 - 220
  • [49] Calculation of LDL-cholesterol by using apolipoprotein B for classification of nonchylomicronemic dyslipemia
    Planella, T
    Cortes, M
    MartinezBru, C
    GonzalezSastre, F
    OrdonezLlanos, J
    CLINICAL CHEMISTRY, 1997, 43 (05) : 808 - 815
  • [50] 'Ultra-low' levels of LDL-cholesterol confer benefit to the endothelium, particularly in subjects with low HDL-cholesterol
    Kuvin, JT
    Patel, AR
    Sliney, KA
    Pandian, NG
    Karas, RH
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 45 (03) : 392A - 393A
12345