A NEW LACTAM PROTECTING GROUP

被引：14
|
作者：
SMITH, MB
WANG, CJ
KEUSENKOTHEN, PF
DEMBOFSKY, BT
FAY, JG
ZEZZA, CA
KWON, TW
SHEU, JL
SON, YC
MENEZES, RF
机构：
来源：
CHEMISTRY LETTERS | 1992年 / 02期
关键词：
D O I：
10.1246/cl.1992.247
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
N-Alkenyl and N-alkoxymethyl lactams are impervious to many reagents and are useful protecting groups for lactams. Conversion to the corresponding 2-ethoxy iminium salt and hydrolysis in neutral water removes the protecting group. Mild basification regenerates the lactam.
引用
收藏
页码：247 / 250
页数：4
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