The results of the development of a new technological process and equipment for the production of trichloride-lutetium-177 at the JSC "Institute of Reactor Materials" are presented. A new technological process is proposed for the production of a radiopharmaceutical precursor of lutetium trichloride 177LuCl3, which comprises more than thirty technological and control operations. New technological equipment has been developed to ensure the implementation of technological operations within the process. The behavior modeling of the devices being developed in high-intensity radiation fields has been carried out.