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CORRECTIONS FOR ACCIDENTAL COINCIDENCES AND ATTENUATION IN MAXIMUM-LIKELIHOOD IMAGE-RECONSTRUCTION FOR POSITRON-EMISSION TOMOGRAPHY
被引:112
|作者:
POLITTE, DG
SNYDER, DL
机构:
[1] Washington University, St. Louis, MO
基金:
美国国家卫生研究院;
美国国家科学基金会;
关键词:
D O I:
10.1109/42.75614
中图分类号:
TP39 [计算机的应用];
学科分类号:
081203 ;
0835 ;
摘要:
A new method has been developed and tested for correcting for the effects of accidental coincidences and photon attenuation in positron-emission tomography. A mathematical model is used for these effects as the basis for the development. The corrections are incorporated into the iterations of an expectation-maximization algorithm for numerically producing the maximum-likelihood estimate of a distribution of radioactivity within a patient. We have found the images reconstructed with this new procedure to be unbiased and to exhibit lower variance than those reconstructed from precorrected data.
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页码:82 / 89
页数:8
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