MULTIVARIATE CALIBRATION FOR PROTEIN, CHOLESTEROL AND TRIGLYCERIDES IN HUMAN PLASMA USING SHORT-WAVE NEAR-INFRARED SPECTROMETRY

被引:41
|
作者
BITTNER, A
MARBACH, R
HEISE, HM
机构
[1] Institut für Spektrochemie und Angewandte Spektroskopie, Dortmund, D-44139
关键词
D O I
10.1016/0022-2860(95)08779-U
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Recent progress in spectroscopy and chemometrics have brought the reagentless analysis of blood substrates by near infrared spectroscopy into clinical reach. Results for the in-vitro analysis of several blood substrates in human blood plasma using multivariate calibration by partial-least squares are presented for 125 hospital samples. Whereas the relative mean-squared prediction error for total protein (1.4%) using short wave NIR data is comparable with previous results using conventional NIR spectroscopy, the errors found for total cholesterol (6.5%) and triglycerides (13.8%) are nearly a factor of two worse for this study.
引用
收藏
页码:341 / 344
页数:4
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