74 patients with non-Hodgkin's lymphoma (NHL) in the head and neck were studied and 21 out of 74 (28.4%) had a primary extranodal location. The most commonly affected lymph nodes were the lateral cervical (48%); the extranodal NHL occurred most frequently in Waldeyer's ring (19%) and orbit (5.4%). Overall 10-year survival was 55.2% with a median survival of 42 months, and survival was higher in extranodal(67.3%) than in nodal locations (51.9%). No statistically significant difference between the survival of high-grade and low-grade tumours was observed. There was, on the contrary, a correlation between stage of the disease and survival of the patients. Most cases were B-cell lymphomas (91.8%). Nodal NHL presented at diagnosis in an advanced stage in a higher percentage (71.2%) than extranodal (48%). High-grade tumours seemed to affect mainly young people.
机构:
Royal Victoria Infirm, Dept Haematol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, EnglandRoyal Victoria Infirm, Dept Haematol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
Mounter, PJ
Lennard, AL
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机构:
Royal Victoria Infirm, Dept Haematol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, EnglandRoyal Victoria Infirm, Dept Haematol, Newcastle Upon Tyne NE1 4LP, Tyne & Wear, England
机构:
Division of Hematology and Oncology, Center for Lymphoma and Myeloma, Cornell University, Ithaca, NYDivision of Hematology and Oncology, Center for Lymphoma and Myeloma, Cornell University, Ithaca, NY
Furman R.R.
Coleman M.
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New York Presbyterian Hospital, New York, NY 10021Division of Hematology and Oncology, Center for Lymphoma and Myeloma, Cornell University, Ithaca, NY
Coleman M.
Leonard J.P.
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New York Presbyterian Hospital, New York, NY 10021Division of Hematology and Oncology, Center for Lymphoma and Myeloma, Cornell University, Ithaca, NY