SYNTHESIS OF NEW FUNGICIDAL IMIDAZO[2,1-B]-1,3-THIAZINONES AND BENZIMIDAZO[2,1-B]-1,3-THIAZINONES INVOLVING RING TRANSFORMATION OF 5-OXAZOLONE DERIVATIVES

被引：14
|
作者：
YADAV, LDS
VAISH, A
机构：
[1] Department of Chemistry, University of Allahabad
来源：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1992年 / 40卷 / 02期
关键词：
D O I：
10.1021/jf00014a026
中图分类号：
S [农业科学];
学科分类号：
09 ;
摘要：
Michael-type addition of 2-imidazolidinethione (Ia) and 2-mercaptobenzimidazole (Ib) to 4-benzylidene-5-oxazolones IIa-e followed by ring transformation of the resulting Michael adducts IIIa-j yielded new compounds, 6-acet(and benz)amido-7-aryl-2,3,6,7-tetrahydro-5H-imidazo[2,1-b]-1,3-thiazin-5-ones IVa-e and 3-acet(and benz)amido-2-aryl-2,3-dihydro-4H-benzimidazo[2,1-b]-1,3-thiazin-4-ones IVa-j, respectively, in one pot. The compounds IIIa, IIIf, IIIi, and IVa-j were compared with Dithane M-45, a commercial fungicide, for their antifungal activity against Aspergillus niger and Fusarium oxysporium, and the results were correlated with the structural features of the tested compounds.
引用
收藏
页码：294 / 296
页数：3
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