Optical frequency domain imaging system and catheters for volumetric imaging of the human esophagus

被引:4
|
作者
Gora, Michalina [1 ,2 ]
Yoo, Hongki [1 ,2 ]
Suter, Melissa J. [1 ,2 ]
Gallagher, Kevin A. [1 ]
Bouma, Brett E. [1 ,2 ,3 ]
Nishioka, Norman S. [1 ,4 ]
Tearney, Guillermo J. [1 ,3 ,5 ]
机构
[1] Massachusetts Gen Hosp, Wellman Ctr Photomed, Boston, MA 02114 USA
[2] Massachusetts Gen Hosp, Harvard Med Sch, Dept Dermatol, Boston, MA 02114 USA
[3] Harvard MIT Div Hlth Sci & Technol, Cambridge, MA USA
[4] Massachusetts Gen Hosp, Harvard Med Sch, Gastrointestinal Unit, Boston, MA 02114 USA
[5] Massachusetts Gen Hosp, Harvard Med Sch, Dept Pathol, Boston, MA 02114 USA
关键词
Tissue - Natural frequencies - Frequency domain analysis - Optical materials;
D O I
10.4302/plp.2011.4.06
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
Barrett's esophagus (BE) is a metaplastic disorder that can undergo dysplastic progression, leading to esophageal adenocarcinoma. Upper endoscopy is the standard of care for screening for BE, but this technique has a relatively low diagnostic accuracy and high cost due to the requirement of conscious sedation. Optical frequency domain imaging (OFDI) is a high-speed imaging modality that generates cross-sectional images of tissues with a resolution of approximately 10 mu m that is sufficient for detecting microscopic tissue architecture. In combination with a balloon-centering catheter, this method enables BE diagnosis over the entire distal esophagus.
引用
收藏
页码:144 / 146
页数:3
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