PHARMACOLOGY OF INTRAVENOUS SEDATIVES AND OPIOIDS IN CRITICALLY ILL PATIENTS

被引：22
|
作者：
LEVINE, RL
机构：
来源：
CRITICAL CARE CLINICS | 1994年 / 10卷 / 04期
关键词：
D O I：
10.1016/S0749-0704(18)30102-7
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
This article summarizes the pharmacologic principles necessary to rationally understand and use sedatives and opioids for the treatment of agitation, delirium, and pain relief in critically ill patients. Benzodiazepines, barbiturates, ketamine, etomidate, propofol, and neuroleptics are all reviewed in detail. In addition, a rational approach to the use of opioid analgesics is presented.
引用
收藏
页码：709 / 731
页数：23
相关论文
共 50 条
  • [1] Comparison of the Effects of Intravenous Sedatives on Outcome in Adult Critically ill Patients: a Bayesian Network Analysis
    Jing-Yuan Xu
    Zong-Sheng Wu
    Wei Chang
    Zhong-Hua Lu
    Yi Yang
    Intensive Care Research, 2022, 2 (1-2): : 12 - 22
  • [2] Use of sedatives in the critically ill
    Peck, Marcus
    Down, Jim
    ANAESTHESIA AND INTENSIVE CARE MEDICINE, 2010, 11 (01): : 12 - 15
  • [3] Why opioids and sedatives may prolong life rather than hasten death after ventilator withdrawal in critically ill patients
    Bakker, Jan
    Jansen, Tim C.
    Lima, Alex
    Kompanje, Erxvin J. O.
    AMERICAN JOURNAL OF HOSPICE & PALLIATIVE MEDICINE, 2008, 25 (02): : 152 - 154
  • [4] Effects of high dose opioids and sedatives on survival in terminally ill cancer patients
    Morita, T
    Tsunoda, J
    Inoue, S
    Chihara, S
    JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 2001, 21 (04) : 282 - 289
  • [5] Pharmacology of the critically ill
    R M Grounds
    Critical Care, 6 (4):
  • [6] Pharmacokinetics and pharmacodynamics of sedatives and analgesics in the treatment of agitated critically ill patients
    Wagner, BKJ
    O'Hara, DA
    CLINICAL PHARMACOKINETICS, 1997, 33 (06) : 426 - 453
  • [7] Pharmacokinetics and Pharmacodynamics of Sedatives and Analgesics in the Treatment of Agitated Critically Ill Patients
    Bertil Wagner
    Dorene A. O’Hara
    Clinical Pharmacokinetics, 1997, 33 : 426 - 453
  • [8] OPIOIDS AND SEDATIVES DO NOT SEEM TO CONTRIBUTE TO TIME TILL DEATH WITHDRAWAL OF LIFE SUSTAINING THERAPY IN DUTCH CRITICALLY ILL ICU PATIENTS
    Epker, J. L.
    Kompanje, E. J. O.
    INTENSIVE CARE MEDICINE, 2012, 38 : S242 - S243
  • [9] Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
    Candelaria de Haro
    Rudys Magrans
    Josefina López-Aguilar
    Jaume Montanyà
    Enrico Lena
    Carles Subirà
    Sol Fernandez-Gonzalo
    Gemma Gomà
    Rafael Fernández
    Guillermo M. Albaiceta
    Yoanna Skrobik
    Umberto Lucangelo
    Gastón Murias
    Ana Ochagavia
    Robert M. Kacmarek
    Montserrat Rue
    Lluís Blanch
    Critical Care, 23
  • [10] Effects of sedatives and opioids on trigger and cycling asynchronies throughout mechanical ventilation: an observational study in a large dataset from critically ill patients
    de Haro, Candelaria
    Magrans, Rudys
    Lopez-Aguilar, Josefina
    Montanya, Jaume
    Lena, Enrico
    Subira, Carles
    Fernandez-Gonzalo, Sol
    Goma, Gemma
    Fernandez, Rafael
    Albaiceta, Guillermo M.
    Skrobik, Yoanna
    Lucangelo, Umberto
    Murias, Gaston
    Ochagavia, Ana
    Kacmarek, Robert M.
    Rue, Montserrat
    Blanch, Lluis
    de Haro, Candelaria
    Lopez-Aguilar, Josefina
    Magrans, Rudys
    Fernandez-Gonzalo, Sol
    Goma, Gemma
    Chacon, Encarna
    Estruga, Anna
    Ochagavia, Ana
    Blanch, Lluis
    Montanya, Jaume
    Sales, Bernat
    Lena, Enrico
    Lucangelo, Umberto
    Fernandez, Rafael
    Subira, Carles
    Albaiceta, Guillermo M.
    Fernandez-Mondejar, Enrique
    Murias, Gaston
    Kacmarek, Robert M.
    CRITICAL CARE, 2019, 23 (1):
12345