PARANEOPLASTIC CEREBELLAR DEGENERATION AND LIMBIC ENCEPHALITIS IN A PATIENT WITH ADENOCARCINOMA OF THE COLON

被引：50
|
作者：
TSUKAMOTO, T
MOCHIZUKI, R
MOCHIZUKI, H
NOGUCHI, M
KAYAMA, H
HIWATASHI, M
YAMAMOTO, T
机构：
[1] TOHOKU UNIV,SCH MED,DEPT NEUROL,SENDAI,MIYAGI 980,JAPAN
[2] FUKUSHIMA MED COLL,DEPT BIOCHEM,FUKUSHIMA 960,JAPAN
[3] TOHOKU UNIV,SCH MED,DEPT INTERNAL MED 3,SENDAI,MIYAGI 980,JAPAN
来源：
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1993年 / 56卷 / 06期
关键词：
D O I：
10.1136/jnnp.56.6.713
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
The rare association of two neurological paraneoplastic syndromes, paraneoplastic cerebellar degeneration and limbic encephalitis occurred in a 55 year old woman with a microscopic adenocarcinoma in a colonic polyp. Complete removal of the tumour by polypectomy brought about a favourable recovery from limbic encephalitis but the cerebellar ataxia remained. High titres of antineuronal nuclear antibody resembling anti-Hu were demonstrated in serum by immunohistochemistry using rat brain as a substrate. The antibody identified a protein band of 41 kDa on a Western immunoblot.
引用
收藏
页码：713 / 716
页数：4
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