IMPACT OF PHOSPHATIDYL CHOLINE CHOLESTEROL LIPOSOMES ON GROWTH OF SOME BACTERIAL CULTURES

被引：0
|
作者：
MELYANTSEVA, LP [1 ]
KREINES, VM [1 ]
MELNIKOVA, VM [1 ]
GLADSHTEIN, AI [1 ]
机构：
[1] NN PRIOROV CENT TRAUMATOL & ORTHOPAED RES INST, MOSCOW, USSR
来源：
ANTIBIOTIKI I KHIMIOTERAPIYA | 1992年 / 37卷 / 01期
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D O I：
暂无
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The in vitro studies showed that incubation of S. aureus, P. aeruginosa, E. coli and P. mirabilis in the presence of phosphatidyl choline cholesterol liposomal suspension was accompanied by inhibited microbial growth. The effect was time- and dose-dependent. The arranged structure of the liposomal membranes played an important role in genesis of the bactericidal action of the liposomes since the use of lipids of the same composition in a nonpolysomal form markedly lowered the bactericidal effect.
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页码：14 / 17
页数：4
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