POTENTIAL BIOACTIVATION PATHWAYS FOR THE NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)

被引：140
|
作者：
CASTAGNOLI, N
CHIBA, K
TREVOR, AJ
机构：
来源：
LIFE SCIENCES | 1985年 / 36卷 / 03期
关键词：
D O I：
10.1016/0024-3205(85)90063-3
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
引用
收藏
页码：225 / 230
页数：6
相关论文
共 50 条
  • [31] Mutagenic activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Ulanowska, K
    Wegrzyn, G
    JOURNAL OF APPLIED GENETICS, 2006, 47 (01) : 85 - 87
  • [32] ASTROCYTIC RESPONSES TO THE DOPAMINERGIC NEUROTOXIN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) IN CAT AND MOUSE-BRAIN
    SCHNEIDER, JS
    DENARO, FJ
    JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY, 1988, 47 (04): : 452 - 458
  • [33] AUTORADIOGRAPHY OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP) - UPTAKE IN THE MONOAMINERGIC PATHWAYS AND IN MELANIN CONTAINING TISSUES
    LYDEN, A
    BONDESSON, U
    LARSSON, BS
    LINDQUIST, NG
    OLSSON, LI
    ACTA PHARMACOLOGICA ET TOXICOLOGICA, 1985, 57 (02): : 130 - 135
  • [34] Metallobiology of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity
    Hare, Dominic J.
    Adlard, Paul A.
    Doble, Philip A.
    Finkelstein, David I.
    METALLOMICS, 2013, 5 (02) : 91 - 109
  • [35] Mutagenic activity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Katarzyna Ulanowska
    Grzegorz Węgrzyn
    Journal of Applied Genetics, 2006, 47 : 85 - 87
  • [36] 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) decreases glutamate uptake in cultured astrocytes
    Hazell, AS
    Itzhak, Y
    Liu, HP
    Norenberg, MD
    JOURNAL OF NEUROCHEMISTRY, 1997, 68 (05) : 2216 - 2219
  • [37] Neurochemical evidence for agmatine modulation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxicity
    Gilad, GM
    Gilad, VH
    Finberg, JPM
    Rabey, JM
    NEUROCHEMICAL RESEARCH, 2005, 30 (6-7) : 713 - 719
  • [38] Chromosomal loci influencing the susceptibility to the parkinsonian neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    Sedelis, M
    Hofele, K
    Schwarting, RKW
    Huston, JP
    Belknap, JK
    JOURNAL OF NEUROSCIENCE, 2003, 23 (23): : 8247 - 8253
  • [39] CHANGES OF THE CONVULSANT RESPONSE IN 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)-TREATED RODENTS
    FARIELLO, RG
    DEMATTEI, M
    GOLDEN, GT
    FERRARO, TN
    NEUROLOGY, 1986, 36 (04) : 96 - 97
  • [40] MECHANISM OF THE NEUROTOXICITY OF 1-METHYL-4-PHENYLPYRIDINIUM (MPP+), THE TOXIC BIOACTIVATION PRODUCT OF 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE (MPTP)
    SINGER, TP
    RAMSAY, RR
    MCKEOWN, K
    TREVOR, A
    CASTAGNOLI, NE
    TOXICOLOGY, 1988, 49 (01) : 17 - 23
12345