SYNTHESIS AND ANTI-HIV ACTIVITY OF VARIOUS 2'-SUBSTITUTED AND 3'-SUBSTITUTED 2',3'-DIDEOXYADENOSINES - A STRUCTURE ACTIVITY ANALYSIS

被引：177
|
作者：
HERDEWIJN, P [1 ]
PAUWELS, R [1 ]
BABA, M [1 ]
BALZARINI, J [1 ]
DECLERCQ, E [1 ]
机构：
[1] CATHOLIC UNIV LEUVEN, REGA INST MED RES, B-3000 LOUVAIN, BELGIUM
来源：
JOURNAL OF MEDICINAL CHEMISTRY | 1987年 / 30卷 / 11期
关键词：
D O I：
10.1021/jm00394a034
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：2131 / 2137
页数：7
相关论文
共 50 条
  • [1] METABOLISM AND ANTI-HIV ACTIVITY OF 2-HALO-2', -3'-DIDEOXYADENOSINES
    HAERTLE, T
    CARRERA, CJ
    MCDOUGAL, JS
    RICHMAN, DD
    CARSON, DA
    JOURNAL OF CELLULAR BIOCHEMISTRY, 1987, : 65 - 65
  • [2] SYNTHESIS OF 4'-SUBSTITUTED 2'-DEOXYNUCLEOSIDES HAVING POTENT ANTI-HIV ACTIVITY
    PRISBE, EJ
    MAAG, H
    RYDZEWSKI, RM
    VERHEYDEN, JPH
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1992, 203 : 28 - CARB
  • [3] SYNTHESIS AND ANTI-HIV ACTIVITY OF 2-SUBSTITUTED 2'-DEOXY-2'-FLUOROADENOSINES
    MARUYAMA, T
    UTSUMI, K
    SATO, Y
    RICHMAN, DD
    NUCLEOSIDES & NUCLEOTIDES, 1994, 13 (6-7): : 1219 - 1230
  • [4] SYNTHESIS AND ANTI-HIV ACTIVITY OF 6-SUBSTITUTED PURINE 2'-DEOXY-2'-FLUORORIBOSIDES
    MARUYAMA, T
    UTZUMI, K
    SATO, Y
    RICHMAN, DD
    NUCLEOSIDES & NUCLEOTIDES, 1994, 13 (1-3): : 527 - 537
  • [5] CORRELATION BETWEEN THE ANTI-HIV ACTIVITY AND ELECTROSTATIC PROPERTIES OF 3'-SUBSTITUTED DEOXYTHYMIDINES
    GRANA, AM
    RIOS, MA
    JOURNAL OF MOLECULAR STRUCTURE-THEOCHEM, 1995, 334 (01): : 37 - 43
  • [6] Synthesis and anti-HIV activity of substituted 1 2,4-triazolo-thiophene derivatives
    Al-Soud, Yaseen A.
    HETEROATOM CHEMISTRY, 2007, 18 (04) : 443 - 448
  • [7] SYNTHESIS AND ANTI-HIV ACTIVITY OF 2-SUBSTITUTED, 3-SUBSTITUTED, AND 4-SUBSTITUTED ANALOGS OF 1-[(2-HYDROXYETHOXY)METHYL]-6-(PHENYLTHIO)THYMINE (HEPT)
    TANAKA, H
    BABA, M
    UBASAWA, M
    TAKASHIMA, H
    SEKIYA, K
    NITTA, I
    SHIGETA, S
    WALKER, RT
    DECLERCQ, E
    MIYASAKA, T
    JOURNAL OF MEDICINAL CHEMISTRY, 1991, 34 (04) : 1394 - 1399
  • [8] Preparation and anti-HIV activity of N-3-substituted thymidine nucleoside analogs
    Adams, DR
    Perez, C
    Maillard, M
    Florent, JC
    Evers, M
    Henin, Y
    Litvak, S
    Litvak, L
    Monneret, C
    Grierson, DS
    JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (10) : 1550 - 1558
  • [9] SYNTHESIS AND ANTI-HIV ACTIVITY OF 4'-THIO-2',3'-DIDEOXYNUCLEOSIDES
    SECRIST, JA
    RIGGS, RM
    TIWARI, KN
    MONTGOMERY, JA
    JOURNAL OF MEDICINAL CHEMISTRY, 1992, 35 (03) : 533 - 538
  • [10] Synthesis and anti-HIV activity of novel 2′,3′-dideoxy-3′-thiacytidine prodrugs
    Ravetti, Soledad
    Gualdesi, Maria S.
    Trinchero-Hernandez, Juan S.
    Turk, Gabriela
    Brinon, Margarita C.
    BIOORGANIC & MEDICINAL CHEMISTRY, 2009, 17 (17) : 6407 - 6413
12345