STRUCTURAL AND FUNCTIONAL-ASPECTS OF CALCIUM HOMEOSTASIS IN EUKARYOTIC CELLS

被引：189
|
作者：
PIETROBON, D
DIVIRGILIO, F
POZZAN, T
机构：
[1] UNIV FERRARA, INST GEN PATHOL, VIA BORSARI 46, I-35121 FERRARA, ITALY
[2] UNIV PADUA, CNR, STUDY PHYSIOL MITOCHONDRIA UNIT, I-35100 PADUA, ITALY
[3] UNIV PADUA, INST GEN PATHOL, I-35100 PADUA, ITALY
来源：
EUROPEAN JOURNAL OF BIOCHEMISTRY | 1990年 / 193卷 / 03期
关键词：
D O I：
10.1111/j.1432-1033.1990.tb19378.x
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
The maintenance of a low cytosolic free‐Ca2+ concentration, ([Ca2+]i) is a common feature of all eukaryotic cells. For this purpose a variety of mechanisms have developed during evolution to ensure the buffering of Ca2+ in the cytoplasm, its extrusion from the cell and/or its accumulation within organelles. Opening of plasma membrane channels or release of Ca2+ from intracellular pools leads to elevation of [Ca2+]i; as a result, Ca2+ binds to cytosolic proteins which translate the changes in [Ca2+]i into activation of a number of key cellular functions. The purpose of this review is to provide a comprehensive description of the structural and functional characteristics of the various components of [Ca2+]i homeostasis in eukaryotes. Copyright © 1990, Wiley Blackwell. All rights reserved
引用
收藏
页码：599 / 622
页数：24
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