DIFFERENTIAL DEVELOPMENT OF ANGIOTENSIN-II RECEPTOR SUBTYPES IN THE RAT-BRAIN

被引：80
|
作者：
TSUTSUMI, K
SAAVEDRA, JM
机构：
[1] Section on Pharmacology, Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, MD
来源：
ENDOCRINOLOGY | 1991年 / 128卷 / 01期
关键词：
D O I：
10.1210/endo-128-1-630
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Angiotensin II receptors in selected brain areas were characterized into two distinct subtypes by displacement with specific antagonists. The receptor subtypes had different developmental patterns. Type-1 receptors, selectively displaced by the specific angiotensin antagonist DuP-753, were predominant in adult (8-weeks-old) rats. Type-2 receptors were selectively displaced by CGP 42112 A and were expressed remarkably in young (2-weeks-old) rats.
引用
收藏
页码：630 / 632
页数：3
相关论文
共 50 条
  • [1] ANGIOTENSIN-II RECEPTOR SUBTYPES IN THE RAT-BRAIN
    ROWE, BP
    GROVE, KL
    SAYLOR, DL
    SPETH, RC
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1990, 186 (2-3) : 339 - 342
  • [2] ANGIOTENSIN-II RECEPTOR SUBTYPES IN RAT-BRAIN
    SONG, KF
    ALLEN, AM
    PAXINOS, G
    MENDELSOHN, FAO
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 1991, 18 (02) : 93 - 96
  • [3] CHARACTERIZATION AND DEVELOPMENT OF ANGIOTENSIN-II RECEPTOR SUBTYPES IN RAT-BRAIN
    TSUTSUMI, K
    SAAVEDRA, JM
    FASEB JOURNAL, 1991, 5 (06): : A1740 - A1740
  • [4] DISTRIBUTION OF ANGIOTENSIN-II RECEPTOR SUBTYPES IN RAT-BRAIN NUCLEI
    OBERMULLER, N
    UNGER, T
    CULMAN, J
    GOHLKE, P
    DEGASPARO, M
    BOTTARI, SP
    NEUROSCIENCE LETTERS, 1991, 132 (01) : 11 - 15
  • [5] DIFFERENTIAL DISTRIBUTION OF AT1 AND AT2 ANGIOTENSIN-II RECEPTOR SUBTYPES IN THE RAT-BRAIN DURING DEVELOPMENT
    MILLAN, MA
    JACOBOWITZ, DM
    AGUILERA, G
    CATT, KJ
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1991, 88 (24) : 11440 - 11444
  • [6] ANGIOTENSIN-II RECEPTOR SUBTYPES IN RAT-BRAIN AND PERIPHERAL-TISSUES
    SONG, K
    ZHUO, J
    ALLEN, AM
    PAXINOS, G
    MENDELSOHN, FAO
    CARDIOLOGY, 1991, 79 : 45 - 54
  • [7] ANALYSIS OF ANGIOTENSIN-II RECEPTOR SUBTYPES IN INDIVIDUAL RAT-BRAIN NUCLEI
    ROWE, BP
    SAYLOR, DL
    SPETH, RC
    NEUROENDOCRINOLOGY, 1992, 55 (05) : 563 - 573
  • [8] CHARACTERIZATION AND DEVELOPMENT OF ANGIOTENSIN-II RECEPTOR SUBTYPES (AT1 AND AT2) IN RAT-BRAIN
    TSUTSUMI, K
    SAAVEDRA, JM
    AMERICAN JOURNAL OF PHYSIOLOGY, 1991, 261 (01): : R209 - R216
  • [9] DIFFERENTIAL REGULATION OF ANGIOTENSIN-II RECEPTOR SUBTYPES IN THE RAT-BRAIN DURING DIETARY-SODIUM CHANGES
    SANDBERG, K
    JI, H
    CATT, KJ
    HYPERTENSION, 1993, 21 (04) : 530 - 530
  • [10] REGIONAL DISTRIBUTION OF THE ANGIOTENSIN-II RECEPTOR IN RAT-BRAIN
    CHEN, FM
    PRINTZ, MP
    FEDERATION PROCEEDINGS, 1981, 40 (03) : 589 - 589
12345