SISTER CHROMATID EXCHANGES IN PATIENTS WITH CARCINOMA INSITU OF CERVIX UTERI

被引：13
|
作者：
LUKOVIC, L
MILASIN, J
机构：
[1] Institute of Biology and Human Genetics, University of Belgrade School of Medicine and Dentistry
来源：
CANCER GENETICS AND CYTOGENETICS | 1992年 / 59卷 / 01期
关键词：
D O I：
10.1016/0165-4608(92)90165-5
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Sister chromatid exchange (SCE) was analyzed in lymphocytes of 21 patients with carcinoma in situ of cervix uteri and 19 control subjects. The mean SCE frequencies were 8.92 +/- 0.31 (n = 417) and 6.94 +/- 0.23, (n = 375) per metaphase in patients and controls, respectively. The increase of SCE levels in cancer patients was highly significant in respect to controls (p < 0.001). Together with data of other authors in patients with precancerous and cancerous lesions of the cervix, our results suggest that there is no correlation between SCE rate and severity of cancerous lesions.
引用
收藏
页码：84 / 85
页数：2
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