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THE CALF SUPEROXIDE-DISMUTASE RECEPTOR OF RAT HEPATOCYTES
被引:8
|作者:
MONDOLA, P
SANTILLO, M
SANTANGELO, F
GARBI, C
DANIELE, A
机构:
[1] UNIV NAPLES FEDERICO II,FAC MED & CHIRURG,DIPARTIMENTO BIOL & PATOL CELLULARE & MOLEC,I-80131 NAPLES,ITALY
[2] UNIV NAPLES FEDERICO II,FAC MED & CHIRURG,DIPARTIMENTO BIOCHIM & BIOTECNOL MED,I-80131 NAPLES,ITALY
来源:
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY B-BIOCHEMISTRY & MOLECULAR BIOLOGY
|
1994年
/
108卷
/
03期
关键词:
SOD;
HMG-COA REDUCTASE;
RAT HEPATOCYTES;
RATTUS BUBALUS;
D O I:
10.1016/0305-0491(94)90082-5
中图分类号:
Q5 [生物化学];
Q7 [分子生物学];
学科分类号:
071010 ;
081704 ;
摘要:
The presence of a specific SOD surface membrane receptor in rat hepatocyte cells was investigated using ligand blot analysis of the SOD receptor with I-125-SOD, and binding studies with iodinated and fluorescinated SOD. A specific SOD receptor with a molecular weight of about 320 kDa was identified. We suggest that the modulatory role of SOD on HMG-CoA reductase is exerted through this specific receptor.
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页码:309 / 313
页数:5
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