EXPERIMENTS DIRECTED TOWARDS THE SYNTHESIS OF ANTHRACYCLINONES .26. THE PREPARATION OF CHIRAL INTERMEDIATES FOR ANTHRACYCLINONE SYNTHESIS

被引：5
|
作者：
BEAUREGARD, DA [1 ]
CAMBIE, RC [1 ]
DANSTED, PC [1 ]
RUTLEDGE, PS [1 ]
WOODGATE, PD [1 ]
机构：
[1] UNIV AUCKLAND,DEPT CHEM,AUCKLAND,NEW ZEALAND
来源：
AUSTRALIAN JOURNAL OF CHEMISTRY | 1995年 / 48卷 / 03期
关键词：
D O I：
10.1071/CH9950669
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(2'R)-1,5-Dimethoxy-2(2'-methyloxiran-2'-y (8), an intermediate for the synthesis of fridamycin E, has been prepared enantioselectively via the diol (15). The diol (15) was prepared in high yield by asymmetric cis-hydroxylation of the alkene (11). The analogous diol (22), a vineomycinone B-2 precursor, was also prepared.
引用
收藏
页码：669 / 676
页数：8
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