SQ 33,961 IS A POTENT, LONG-ACTING, ORALLY ACTIVE THROMBOXANE RECEPTOR ANTAGONIST WITH WEAK THROMBOXANE A SYNTHASE INHIBITORY ACTIVITY

被引:0
|
作者
OGLETREE, ML [1 ]
HARRIS, DN [1 ]
SCHUMACHER, WA [1 ]
GOLDENBERG, HJ [1 ]
MICHEL, IM [1 ]
OKEEFE, EH [1 ]
ALLEN, GT [1 ]
HERAN, CL [1 ]
STEINBACHER, TE [1 ]
机构
[1] BRISTOL MYERS SQUIBB PHARMACEUT RES INST,PRINCETON,NJ
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:1143 / 1143
页数:1
相关论文
共 32 条
  • [31] Bronchodilator Activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a Potent, Long-Acting, and Selective Muscarinic M3 Receptor Antagonist
    Villetti, G.
    Pastore, F.
    Bergamaschi, M.
    Bassani, F.
    Bolzoni, P. T.
    Battipaglia, L.
    Amari, G.
    Rizzi, A.
    Delcanale, M.
    Volta, R.
    Cenacchi, V.
    Cacciani, F.
    Zaniboni, M.
    Berti, F.
    Rossoni, G.
    Harrison, S.
    Petrillo, P.
    Santoro, E.
    Scudellaro, R.
    Mannini, F.
    Geppetti, P. A.
    Razzetti, R.
    Patacchini, R.
    Civelli, M.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 335 (03): : 622 - 635
  • [32] New orally active non-peptide fibrinogen receptor (GpIIb-IIIa) antagonists: Identification of ethyl 3-[N-[4-[4-[amino[(ethoxycarbonyl)imino]methyl]phenyl]-1,3-thiazol-2-yl]-N-[1-[(ethoxycarbonyl)methyl]piperid-4-yl]amino]propionate (SR 121787) as a potent and long-acting antithrombotic agent
    Badorc, A
    Bordes, MF
    deCointet, P
    Savi, P
    Bernat, A
    Lale, A
    Petitou, M
    Maffrand, JP
    Herbert, JM
    JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (21) : 3393 - 3401