CYCLOCONDENSATION OF NOVEL THIAZOLO[3,2-A]BENZIMIDAZOLES

被引：0
|
作者：
SARHAN, AAO
HOZIEN, ZA
ELSHERIEF, HAH
MAHMOUD, AM
机构：
来源：
POLISH JOURNAL OF CHEMISTRY | 1995年 / 69卷 / 11期
关键词：
THIAZOLO[3,2-A]BENZIMIDAZOLE; OXAZINE; CYCLOCONDENSATION WITH CARBOXYLIC ACIDS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
3-Aminothiazolo[3,2-a]benzimidazole-2-carboxamide (2) was synthesized and cyclized with aliphatic and aromatic acids or with their chlorides to give compounds 3a, and 3b respectively Thiazolo[3,2-a] benzimidazole 1 was cyclized to oxazine-4 which reacted with NH4OH, hydrazinehydrate, ethyl amine and methyl amine hydrochloride to give the corresponding 3a, 5, and 6. Cyclocondensation of 1 with phenylacetic acid gave the cyclized product 7, while the reaction of 1 with o-phenylenediamine in acidic medium afforded 8.
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页码：1479 / 1483
页数：5
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