STUDIES ON BETA-LACTAM ANTIBIOTICS .9. SYNTHESIS AND BIOLOGICAL-ACTIVITY OF A NEW ORALLY ACTIVE CEPHALOSPORIN, CEFIXIME (FK027)

被引：94
|
作者：
YAMANAKA, H
CHIBA, T
KAWABATA, K
TAKASUGI, H
MASUGI, T
TAKAYA, T
机构：
来源：
JOURNAL OF ANTIBIOTICS | 1985年 / 38卷 / 12期
关键词：
D O I：
10.7164/antibiotics.38.1738
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页码：1738 / 1751
页数：14
相关论文
共 50 条
  • [31] 2-SUBSTITUTED PENEMS WITH AMINO ACID-RELATED SIDE-CHAINS - SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF A NEW SERIES OF BETA-LACTAM ANTIBIOTICS
    ALTAMURA, M
    PERROTTA, E
    SBRACI, P
    PESTELLINI, V
    ARCAMONE, F
    CASCIO, G
    LORENZI, L
    SATTA, G
    MORANDOTTI, G
    SPERNING, R
    JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (21) : 4244 - 4256
  • [32] Studies on beta-lactam antibiotics. Synthesis and antibacterial activity of novel 1 beta-methylcarbapenems related to FR21818: 5-membered ring analogs
    Azami, H
    Barrett, D
    Tanaka, A
    Sasaki, H
    Matsuda, K
    Sakurai, M
    Matsumoto, Y
    Tawara, S
    Chiba, T
    Sakane, K
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 1997, 7 (11) : 1409 - 1414
  • [33] ANALYTICAL STUDIES ON BETA-LACTAM ANTIBIOTICS .3. AUTOMATED HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC METHOD FOR THE DETERMINATION OF THE ORALLY ACTIVE ANTIBIOTIC CEFTIBUTEN IN HUMAN-PLASMA AND URINE
    MATSUURA, A
    NAGAYAMA, T
    KITAGAWA, T
    JOURNAL OF CHROMATOGRAPHY-BIOMEDICAL APPLICATIONS, 1989, 494 : 231 - 245
  • [34] STUDIES ON BETA-LACTAM ANTIBIOTICS FOR MEDICINAL PURPOSE .9. STRUCTURE-ACTIVITY-RELATIONSHIPS OF 7-[D(-)-ALPHA-(4-ETHYL-2,3-DIOXO-1-PIPERAZINECARBOXAMIDO)-PHENYLACETAMIDO]CEPHALOSPORANIC ACIDS
    SAIKAWA, I
    YASUDA, T
    TAKI, H
    WATANABE, Y
    TAI, M
    MATSUBARA, N
    TAKAHATA, M
    FUKUOKA, Y
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1979, 99 (11): : 1073 - 1080
  • [35] STUDIES ON BETA-LACTAM ANTIBIOTICS .13. SYNTHESIS AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF 7-BETA-[(Z)-2-ARYL-2-CARBOXYMETHOXYIMINOACETAMIDO]-3-VINYLCEPHALOSPORINS
    KAWABATA, K
    YAMANAKA, H
    TAKASUGI, H
    TAKAYA, T
    JOURNAL OF ANTIBIOTICS, 1986, 39 (03): : 404 - 414
  • [36] STUDIES ON BETA-LACTAM ANTIBIOTICS FOR MEDICINAL PURPOSE .1. SYNTHESIS OF D(-)-ALPHA-[(MONOOXO)-1-PIPERAZINECARBOXAMIDO]BENZYLPENICILLINS AND STRUCTURE-ANTIBACTERIAL ACTIVITY
    SAIKAWA, I
    TAKANO, S
    YOSHIDA, C
    TAKASHIMA, O
    MOMONOI, K
    YASUDA, T
    KASUYA, K
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1977, 97 (08): : 883 - 889
  • [37] STUDIES ON BETA-LACTAM ANTIBIOTICS .2. SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF CEPHALOSPORINS WITH SUBSTITUTED 1,3-DITHIETANE DIRECTLY ATTACHED TO THE C-3 POSITION
    NAGANO, N
    NAKANO, K
    SHIBANUMA, T
    HARA, R
    JOURNAL OF ANTIBIOTICS, 1991, 44 (04): : 415 - 421
  • [38] STUDIES ON BETA-LACTAM ANTIBIOTICS FOR MEDICINAL PURPOSE .2. SYNTHESIS OF D(-)-ALPHA-[DIOXO-1-PIPERAZINECARBOXAMIDO]BENZYLPENICILLINS AND STRUCTURE-ANTIBACTERIAL ACTIVITY
    SAIKAWA, I
    TAKANO, S
    YOSHIDA, C
    TAKASHIMA, O
    MOMONOI, K
    YASUDA, T
    KASUYA, K
    KOMATSU, M
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1977, 97 (09): : 980 - 986
  • [39] HETEROATOM-ACTIVATED BETA-LACTAM ANTIBIOTICS - CONSIDERATIONS OF DIFFERENCES IN THE BIOLOGICAL-ACTIVITY OF [[3(S)-(ACYLAMINO)-2-OXO-1-AZETIDINYL]OXY]ACETIC ACIDS (OXAMAZINS) AND THE CORRESPONDING SULFUR ANALOGS (THIAMAZINS)
    BOYD, DB
    EIGENBROT, C
    INDELICATO, JM
    MILLER, MJ
    PASINI, CE
    WOULFE, SR
    JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (03) : 528 - 536
  • [40] STUDIES ON BETA-LACTAM ANTIBIOTICS .5. SYNTHESIS OF 6-[D(-)-ALPHA-(ACYLAMINO)-4-HYDROXYPHENYLACETAMIDO]PENICILLANIC ACIDS AND ANTI-BACTERIAL ACTIVITY
    TOBIKI, H
    YAMADA, H
    TANNO, N
    SHIMAGO, K
    EDA, Y
    NOGUCHI, H
    KOMATSU, T
    NAKAGOME, T
    YAKUGAKU ZASSHI-JOURNAL OF THE PHARMACEUTICAL SOCIETY OF JAPAN, 1980, 100 (02): : 133 - 139
12345