Complete Hydatidiform Mole in a Postmenopausal Woman

Background: Postmenopausal gestational trophoblastic neoplasia (GTN) is extremely rare. Because of its rarity and benign nature, a case is presented here. Case: A 51-year-old woman presented with bleeding per vaginum. Ultrasound of her pelvis revealed a mixed solid and cystic mass-like structure and no adnexal pathology. Other systemic examinations revealed no other abnormalities. A presumptive diagnosis of hydatidiform mole was made. Total abdominal hysterectomy and bilateral oophorectomy were performed. Results: The specimen consisted of a 15 cm x11 cm x 8 cm uterus with bilateral Fallopian tubes and ovaries. The histomorphologic findings were suggestive of benign noninvasive complete mole. Follow-up showed no evidence of GTN. Conclusions: Although rare, the diagnosis of hydatidiform mole should be kept in mind when evaluating patients with postmenopausal bleeding.