The importance of a general theory of disease is examined. From a definition of a living organism, postulations are made and the concept of related feedback loops introduced. Organisms are considered as closed sets of negative feedbacks, which is presented as the basis for any theory of pathology on which a theory of medicine is developed.
机构:
Inst Pasteur, Microenvironm & Immun Unit, F-75724 Paris, France
INSERM, Unite 1224, F-75724 Paris, FranceInst Pasteur, Microenvironm & Immun Unit, F-75724 Paris, France
Eberl, Gerard
Pradeu, Thomas
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机构:
Ctr Natl Rech Sci CNRS, Unite Mixte Rech 5164, ImmunoConcept, F-33076 Bordeaux, France
Univ Bordeaux, F-33076 Bordeaux, FranceInst Pasteur, Microenvironm & Immun Unit, F-75724 Paris, France