MURINE CD38 - AN IMMUNOREGULATORY ECTOENZYME

被引：84
|
作者：
LUND, F [1 ]
SOLVASON, N [1 ]
GRIMALDI, JC [1 ]
PARKHOUSE, RME [1 ]
HOWARD, M [1 ]
机构：
[1] INST ANIM HLTH,DIV IMMUNOL,WOKING GU24 0NF,SURREY,ENGLAND
来源：
IMMUNOLOGY TODAY | 1995年 / 16卷 / 10期
关键词：
D O I：
10.1016/0167-5699(95)80029-8
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
CD38 is an ectoenxyme that utilizes NAD(+) and is expressed by many cells of hematopoietic origin. Antibodies to CD38 Potentiate many biological activities on lymphocytes, including induction of murine B-cell proliferation. In this article, Frances Lund and colleagues summarize information concerning the expression, enzymatic activity and signal transduction pathway utilized by murine CD38.
引用
收藏
页码：469 / 473
页数：5
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