VOLTAMMETRIC BEHAVIOR OF CAPTOPRIL AND ITS POLAROGRAPHIC-DETERMINATION IN PHARMACEUTICAL FORMS

被引：0
|
作者：
SQUELLA, JA
LEMUS, I
BORGES, Y
NUNEZVERGARA, LJ
机构：
来源：
BOLETIN DE LA SOCIEDAD CHILENA DE QUIMICA | 1992年 / 37卷 / 04期
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Captopril, a potent antihypertensive agent, produces an anodic polarographic peak due to the reaction of its thiol group with the mercury electrode according to the following well-known general pathway for thiol group: RSH + Hg <-> RSHg + H+ + e-The polarographic response is influenced by strong adsorption of reactant, however, the peak current shows a linear dependence with captopril concentration in a wide range. A d.p. polarographic method in order to quantify captopril in commercial tablets is proposed and its result is compared with an UV spectrophotometric method at 210 nm.
引用
收藏
页码：259 / 265
页数：7
相关论文
共 50 条
  • [21] DIFFERENTIAL-PULSE POLAROGRAPHIC-DETERMINATION OF NIZATIDINE IN PHARMACEUTICAL FORMULATIONS
    KAPETANOVIC, V
    MILOVANOVIC, L
    VLADIMIROV, S
    FARMACO, 1994, 49 (05): : 377 - 379
  • [22] POLAROGRAPHIC-DETERMINATION OF DOXORUBICIN AND DAUNORUBICIN IN PHARMACEUTICAL PREPARATIONS AND BIOLOGICAL MEDIA
    GOLABI, SM
    NEMATOLLAHI, D
    JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, 1992, 10 (10-12) : 1053 - 1057
  • [23] RELATION OF AMINOMALONALDEHYDE TO REDUCTONES AND ITS POLAROGRAPHIC-DETERMINATION
    KRUPICKA, J
    ARNOLD, Z
    COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS, 1977, 42 (06) : 1866 - 1870
  • [24] POLAROGRAPHIC-DETERMINATION OF TIN AS ITS THIOCYANATE COMPLEX
    VASILEVA, LN
    YUSTUS, ZL
    ROZHKOVA, LS
    ZASADYCH, SG
    JOURNAL OF ANALYTICAL CHEMISTRY OF THE USSR, 1978, 33 (08): : 1221 - 1225
  • [25] Determination of captopril in pharmaceutical forms by stripping voltammetry
    G. K. Ziyatdinova
    G. K. Budnikov
    V. I. Pogorel’tsev
    Journal of Analytical Chemistry, 2006, 61 : 798 - 800
  • [26] Determination of captopril in pharmaceutical forms by stripping voltammetry
    Ziyatdinova, G. K.
    Budnikov, G. K.
    Pogorel'tsev, V. I.
    JOURNAL OF ANALYTICAL CHEMISTRY, 2006, 61 (08) : 798 - 800
  • [27] Voltammetric behavior of zaleplon and its differential pulse polarographic determination in capsules
    Larenas, G
    Bollo, S
    Rodriguez, M
    Lemus, I
    Nuñez-Vergara, LJ
    Squella, JA
    Alvarez-Lueje, A
    JOURNAL OF AOAC INTERNATIONAL, 2005, 88 (04) : 1135 - 1141
  • [28] Voltammetric behavior of lercanidipine and its differential pulse polarographic determination in tablets
    Alvarez-Lueje, A
    Núñez-Vergara, LJ
    Pujol, S
    Squella, JA
    ELECTROANALYSIS, 2002, 14 (15-16) : 1098 - 1104
  • [29] POLAROGRAPHIC-DETERMINATION OF TROPOLONES
    PROKSA, B
    FUSKA, J
    CHEMICKE ZVESTI, 1974, 28 (06): : 789 - 791
  • [30] POLAROGRAPHIC-DETERMINATION OF TRIALKYLAMINES
    PRIBYL, M
    SEMENKOVA, L
    FRESENIUS ZEITSCHRIFT FUR ANALYTISCHE CHEMIE, 1976, 278 (05): : 347 - 351
12345