Yunpi Xiefei Huatan decoction alleviates airway inflammation and mucus hypersecretion in young asthmatic rats via inhibiting PI3K/AKT/NF-κB signaling pathway

被引：0
|
作者：
王文洲
机构：
[1] 2nd Clin Med Coll
[2] Guizhou CM Univ
来源：
ChinaMedicalAbstracts(InternalMedicine) | 2023年 / 40卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R285.5 [中药实验药理];
学科分类号：
摘要：
Objective To explore the effect of Yunpi Xiefei Huatan Decoction (YXHD) on airway inflammation and mucus hypersecretion in young asthmatic rats based on the correlation of interleukin (IL)-23/T helper cell(Th17) inflammation axis and phosphatidylinositol 3kinase (PI3K)/protein kinase B(AKT)/nuclear factor kappa-B(NF-κB) signal axis.Methods Fifty-six young SD rats were randomly divided into 7 groups:normal group,model group,low-dose group of YXHD(LTCM),
引用
收藏
页码：199 / 200
页数：2
相关论文
共 50 条
  • [21] Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways
    Liao, Zhiheng
    Su, Deying
    Liu, Hengyu
    Xu, Caixia
    Wu, Jinna
    Chen, Yuyu
    Guo, Weimin
    Zhang, Shun
    Li, Zhuling
    Ke, Xiaona
    Wang, Tingting
    Zhou, Taifeng
    Su, Peiqiang
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
  • [22] Baicalin and baicalein attenuate hyperuricemic nephropathy via inhibiting PI3K/AKT/NF-κB signalling pathway
    Liu, Ziyuan
    Xiang, Huilong
    Deng, Qin
    Fu, Wanting
    Li, Yang
    Yu, Zejun
    Qiu, Yinsheng
    Mei, Zhinan
    Xu, Lingyun
    NEPHROLOGY, 2023, 28 (06) : 315 - 327
  • [23] Cannabidiol Alleviates Oral Mucositis by Inhibiting PI3K/Akt/NF- K B- Mediated Pyroptosis
    Yang, Jialin
    Lin, Na
    Li, Shuang
    Dong, Zhanhai
    Wang, Deli
    Liu, Yong
    Zhou, Yang
    Yuan, Hui
    BALKAN MEDICAL JOURNAL, 2024, 41 (04) : 286 - 297
  • [24] Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF- κ B Signaling Pathway
    Li, Xin
    Huang, Songli
    Zhuo, Bingyu
    Hu, Jingyan
    Shi, Yue
    Zhao, Jiangyi
    Tang, Jincheng
    Hu, Xiuhua
    Wei, Shengli
    Oxidative Medicine and Cellular Longevity, 2022, 2022
  • [25] Lentinan attenuates allergic airway inflammation and epithelial barrier dysfunction in asthma via inhibition of the PI3K/AKT/NF-κB pathway
    Song, Yansha
    Chen, Yu
    Cai, Hui
    Zhu, Guiping
    Zeng, Yingying
    Abuduxukuer, Zilinuer
    Chen, Ke
    Wang, Jian
    Ye, Ling
    Jin, Meiling
    PHYTOMEDICINE, 2024, 134
  • [26] Effect of Panax japonicus polysaccharide on acute liver injury rats via PI3K/AKT/NF-κB signaling pathway
    Song, Tianli
    Tang, Lang
    Wang, Yiming
    Wu, Guangyang
    Liu, Xu
    Huang, Sheng
    Jingxi Huagong/Fine Chemicals, 2023, 40 (11): : 2472 - 2479
  • [27] Comparison of Three Species of Rhubarb in Inhibiting Vascular Endothelial Injury via Regulation of PI3K/AKT/NF-κB Signaling Pathway
    Li, Xin
    Huang, Songli
    Zhuo, Bingyu
    Hu, Jingyan
    Shi, Yue
    Zhao, Jiangyi
    Tang, Jincheng
    Hu, Xiuhua
    Wei, Shengli
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2022, 2022
  • [28] Isorhamnetin ameliorates hyperuricemia by regulating uric acid metabolism and alleviates renal inflammation through the PI3K/AKT/NF-κB signaling pathway
    Kong, Xiaoran
    Zhao, Li
    Huang, He
    Kang, Qiaozhen
    Lu, Jike
    Zhu, Jiaqing
    FOOD & FUNCTION, 2025, 16 (07) : 2840 - 2856
  • [29] Calycosin mitigates chondrocyte inflammation and apoptosis by inhibiting the PI3K/AKT and NF-ΚB pathways
    Shi, Xiaoqing
    Jie, Lishi
    Wu, Peng
    Zhang, Nongshan
    Mao, Jun
    Wang, Peimin
    Yin, Songjiang
    JOURNAL OF ETHNOPHARMACOLOGY, 2022, 297
  • [30] Suzi Daotan Decoction alleviates asthmatic airway remodeling through the AMPK/SIRT1/PGC-1α signaling pathway and PI3K/AKT signaling pathway
    Liu, Kaiyue
    Liu, Ruobai
    Zhang, Chenghao
    Huang, Dandan
    Wei, Bowen
    Song, Yilan
    Wang, Chongyang
    Zhang, Xin
    Zheng, Mingyu
    Yan, Guanghai
    SCIENTIFIC REPORTS, 2025, 15 (01):
12345