The adult Drosophila posterior midgut is maintained by pluripotent stem cells

被引:0
|
作者
Benjamin Ohlstein
Allan Spradling
机构
[1] Carnegie Institution of Washington,Howard Hughes Medical Institute Research Laboratories, Department of Embryology
来源
Nature | 2006年 / 439卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
In vertebrates, the cells of the intestine are continually replenished by multipotent stem cells. The discovery of a similar regime in the fruitfly Drosophila has come as a surprise, but a welcome one. With such a well developed genetic model to hand, it should be possible to make great strides in the study of normal and abnormal intestinal function.
引用
收藏
页码:470 / 474
页数:4
相关论文
共 50 条
  • [41] No Intestinal Stem Cell Regeneration after Complete Progenitor Ablation in Drosophila Adult Midgut
    Yanfen Lu
    Zhouhua Li
    Journal of Genetics and Genomics, 2015, 42 (02) : 83 - 86
  • [42] Induced pluripotent stem cells from adult testis: a new source of stem cells?
    Skutella, Thomas
    REGENERATIVE MEDICINE, 2009, 4 (01) : 3 - 5
  • [43] The posterior determinant gene nanos is required for the maintenance of the adult germline stem cells during Drosophila oogenesis
    Bhat, KM
    GENETICS, 1999, 151 (04) : 1479 - 1492
  • [44] Reserve pluripotent stem cells resembling embryonic stem cells are present in adult humans
    Young, HE
    Lucas, PA
    Yoder, MC
    Hixson, DC
    Bray, RA
    Hudson, JA
    Black, AC
    MOLECULAR BIOLOGY OF THE CELL, 2000, 11 : 408A - 408A
  • [45] From skin to pluripotent stem cells: reprogramming of adult somatic cells
    Blum, H. E.
    DEUTSCHE MEDIZINISCHE WOCHENSCHRIFT, 2007, 132 (51-52) : 2774 - 2776
  • [46] Conserved Mechanisms of Tumorigenesis in the Drosophila Adult Midgut
    Martorell, Oscar
    Merlos-Suarez, Anna
    Campbell, Kyra
    Barriga, Francisco M.
    Christov, Christo P.
    Miguel-Aliaga, Irene
    Batlle, Eduard
    Casanova, Jordi
    Casali, Andreu
    PLOS ONE, 2014, 9 (02):
  • [47] The Phoenix of stem cells: pluripotent cells in adult tissues and peripheral blood
    Cancedda, Ranieri
    Mastrogiacomo, Maddalena
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2024, 12
  • [48] Motile stem cells exhibit tissue-level spatial order during homeostasis but not growth of the adult Drosophila midgut.
    Du, X.
    Martin, J.
    Balachandra, S.
    Ngo, S.
    Riedel-Kruse, I.
    O'Brien, L. E.
    MOLECULAR BIOLOGY OF THE CELL, 2016, 27
  • [49] Species-specific developmental timing is maintained by pluripotent stem cells ex utero
    Barry, Christopher
    Schmitz, Matthew T.
    Jiang, Peng
    Schwartz, Michael P.
    Duffin, Bret M.
    Swanson, Scott
    Bacher, Rhonda
    Bolin, Jennifer M.
    Elwell, Angela L.
    Mclntosh, Brian E.
    Stewart, Ron
    Thomson, James A.
    DEVELOPMENTAL BIOLOGY, 2017, 423 (02) : 101 - 110
  • [50] Generation of pluripotent stem cells from adult human testis
    Sabine Conrad
    Markus Renninger
    Jörg Hennenlotter
    Tina Wiesner
    Lothar Just
    Michael Bonin
    Wilhelm Aicher
    Hans-Jörg Bühring
    Ulrich Mattheus
    Andreas Mack
    Hans-Joachim Wagner
    Stephen Minger
    Matthias Matzkies
    Michael Reppel
    Jürgen Hescheler
    Karl-Dietrich Sievert
    Arnulf Stenzl
    Thomas Skutella
    Nature, 2008, 456 : 344 - 349