FMRFamide neuropeptides and acetylcholine synergistically inhibit egg-laying by C. elegans

被引:0
|
作者
Niels Ringstad
H Robert Horvitz
机构
[1] Howard Hughes Medical Institute,Department of Biology
[2] McGovern Institute for Brain Research,undefined
[3] 68-425,undefined
[4] Massachusetts Institute of Technology,undefined
来源
Nature Neuroscience | 2008年 / 11卷
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摘要
Employing molecular genetic analysis of a G protein–coupled receptor and its cognate ligands, Ringstad and Horvitz describe a neuropeptide pathway that modulates egg-laying behavior in C. elegans. This signaling pathway is shown to act in a collaborative fashion with cholinergic signaling to inhibit this behavior.
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页码:1168 / 1176
页数:8
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