Geographic Analysis of the Safety and Efficacy of Filgotinib in Rheumatoid Arthritis

被引：0
|
作者：
Bernard Combe
Robin Besuyen
Antonio Gómez-Centeno
Tsukasa Matsubara
Juan José Sancho Jimenez
Zhaoyu Yin
Maya H. Buch
机构：
[1] University of Montpellier,NIHR Manchester Biomedical Research Centre
[2] Galapagos BV,undefined
[3] Hospital Universitari Parc Tauli,undefined
[4] Sabadell,undefined
[5] Matsubara Mayflower Hospital,undefined
[6] Galapagos,undefined
[7] Gilead Sciences,undefined
[8] Inc.,undefined
[9] University of Manchester,undefined
来源：
Rheumatology and Therapy | 2023年 / 10卷
关键词：
Adverse effects; Disease-modifying antirheumatic drug; Filgotinib; Outcomes; Rheumatoid arthritis;
D O I：
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中图分类号：
学科分类号：
摘要：
Clinical trials in rheumatoid arthritis recruit too few patients from diverse ethnic backgrounds to be able to identify differences in treatment outcomes. In adults with moderate-to-severe active rheumatoid arthritis who do not tolerate or have responded poorly to other advanced treatments, the Janus kinase inhibitor filgotinib can be used alone or in combination with the immunosuppressant methotrexate. Using data from 4695 patients with rheumatoid arthritis from five previous clinical trials and two ongoing trial extensions, this paper examined the efficacy and safety of filgotinib in patients with rheumatoid arthritis across geographic locations worldwide.
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页码：35 / 51
页数：16
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