Absence of the MGMT protein as well as methylation of the MGMT promoter predict the sensitivity for temozolomide

被引:0
|
作者
K A van Nifterik
J van den Berg
W F van der Meide
N Ameziane
L E Wedekind
R D M Steenbergen
S Leenstra
M V M Lafleur
B J Slotman
L J A Stalpers
P Sminia
机构
[1] VU University Medical Center,Department of Radiation Oncology
[2] VU University Medical Center,Department of Pathology
[3] VU University Medical Center,Department of Clinical Genetics
[4] St Elisabeth Ziekenhuis,Department of Neurosurgery
[5] Academic Medical Center,Department of Radiotherapy
来源
British Journal of Cancer | 2010年 / 103卷
关键词
MGMT; temozolomide; glioma; prediction;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:29 / 35
页数:6
相关论文
共 50 条
  • [31] Recurrent PNET with MGMT Methylation Responds to Temozolomide
    Oh, Jiwon
    Bilbao, Juan M.
    Tsao, May N.
    Fazl, Mahmood
    Guiot, Marie-Christine
    Del Maestro, Rolando F.
    Perry, James R.
    CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES, 2009, 36 (05) : 654 - 657
  • [32] MGMT promoter methylation in malignant gliomas
    Riemenschneider, Markus J.
    Hegi, Monika E.
    Reifenberger, Guido
    TARGETED ONCOLOGY, 2010, 5 (03) : 161 - 165
  • [33] MGMT promoter methylation in malignant gliomas
    Markus J. Riemenschneider
    Monika E. Hegi
    Guido Reifenberger
    Targeted Oncology, 2010, 5 : 161 - 165
  • [34] MGMT promoter methylation in pediatric rhabdomyosarcoma
    Ewesuedo, R
    Yeager, N
    Frick, J
    Gastier-Foster, J
    PEDIATRIC RESEARCH, 2002, 51 (04) : 246A - 246A
  • [35] MGMT Promoter Methylation and Parathyroid Carcinoma
    Storvall, Sara
    Ryhanen, Eeva
    Heiskanen, Ilkka
    Vesterinen, Tiina
    Bensch, Frank, V
    Schildt, Jukka
    Kytola, Soili
    Karhu, Auli
    Arola, Johanna
    Schalin-Jantti, Camilla
    JOURNAL OF THE ENDOCRINE SOCIETY, 2019, 3 (11) : 2114 - 2122
  • [36] MGMT Promoter Methylation effects on Esophageal Cancer when treated with Radiation Therapy and Temozolomide
    Pytynia, M. L.
    Herman, L.
    Chaudhary, A.
    Darga, T. E.
    Salgia, R.
    Salama, J.
    Chmura, S. J.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2010, 78 (03): : S633 - S633
  • [37] MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome
    J C Hassel
    A Sucker
    L Edler
    H Kurzen
    I Moll
    C Stresemann
    K Spieth
    C Mauch
    K Rass
    R Dummer
    D Schadendorf
    British Journal of Cancer, 2010, 103 : 820 - 826
  • [38] MGMT gene promoter methylation correlates with tolerance of temozolomide treatment in melanoma but not with clinical outcome
    Hassel, J. C.
    Sucker, A.
    Edler, L.
    Kurzen, H.
    Moll, I.
    Stresemann, C.
    Spieth, K.
    Mauch, C.
    Rass, K.
    Dummer, R.
    Schadendorf, D.
    BRITISH JOURNAL OF CANCER, 2010, 103 (06) : 820 - 826
  • [39] A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation
    Calegari, M. A.
    Inno, A.
    Monterisi, S.
    Orlandi, A.
    Santini, D.
    Basso, M.
    Cassano, A.
    Martini, M.
    Cenci, T.
    de Pascalis, I.
    Camarda, F.
    Barbaro, B.
    Larocca, L. M.
    Gori, S.
    Tonini, G.
    Barone, C.
    BRITISH JOURNAL OF CANCER, 2017, 116 (10) : 1279 - 1286
  • [40] A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation
    M A Calegari
    A Inno
    S Monterisi
    A Orlandi
    D Santini
    M Basso
    A Cassano
    M Martini
    T Cenci
    I de Pascalis
    F Camarda
    B Barbaro
    L M Larocca
    S Gori
    G Tonini
    C Barone
    British Journal of Cancer, 2017, 116 : 1279 - 1286