Amphiphilic conjugates of β-cyclodextrin with acetylsalicylic and 2-(4-isobutylphenyl)propionic acids

被引:0
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作者
M. A. Malenkovskaya
M. K. Grachev
I. I. Levina
E. E. Nifant’ev
机构
[1] Moscow State Pedagogical University,
来源
关键词
Cyclodextrin; Acid Chloride; Sodium Hydride; Propionyl; Secondary Hydroxy Group;
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摘要
New amphiphilic β-cyclodextrin derivatives containing pharmacologically important aromatic and aliphatic monocarboxylic acid fragments at both primary and secondary hydroxy groups were synthesized with the use of palmitic, acetylsalicylic, and 2-(4-isobutylphenyl)propionic acid chlorides. The position of the acyl groups in the carbohydrate fragments of β-cyclodextrin was determined by 13C NMR spectroscopy.
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页码:1777 / 1782
页数:5
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