Epigenetic silencing of the tumor-suppressing gelsolin gene involves histone deacetylation of its promoter region in human urinary bladder cancer

被引：0
|
作者：
Haga K. [1 ,2 ]
Fujita H. [1 ]
Sazawa A. [1 ,2 ]
Takimoto M. [1 ]
Shinohara N. [2 ]
Koyanagi T. [2 ]
Kuzumaki N. [1 ]
机构：
[1] Division of Cancer Gene Regulation, Institute for Genetic Medicine, Hokkaido University, Hokkaido
[2] Department of Urology, School of Medicine, Hokkaido University, Hokkaido
来源：
Nature Genetics | 2001年 / 27卷 / Suppl 4期
关键词：
D O I：
10.1038/87162
中图分类号：
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：66 / 66
相关论文
共 38 条
  • [31] Sequence-specific epigenetic variation in the TNS3 gene promoter and its relation to Tensin3 expression in human kidney cancer
    Carter, J.
    Ljungberg, B.
    Hafizi, S.
    FEBS JOURNAL, 2012, 279 : 486 - 486
  • [32] Structure and methylation-based silencing of a gene (DBCCR1) within a candidate bladder cancer tumor suppressor region at 9q32-q33
    Habuchi, T
    Luscombe, N
    Elder, PA
    Knowles, MA
    GENOMICS, 1998, 48 (03) : 277 - 288
  • [33] Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer
    Song, In-Sung
    Ha, Ga-Hee
    Kim, Jeong-Min
    Jeong, So-Young
    Lee, Han-Chul
    Kim, Yong Sung
    Kim, Yung-Jin
    Kwon, Taeg Kyu
    Kim, Nam-Soon
    INTERNATIONAL JOURNAL OF CANCER, 2011, 129 (09) : 2124 - 2133
  • [34] ESR1 gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients
    Martinez-Galan, Joaquina
    Torres-Torres, Blanca
    Isabel Nunez, Maria
    Lopez-Penalver, Jesus
    Del Moral, Rosario
    Ruiz De Almodovar, Jose Mariano
    Menjon, Salomon
    Concha, Angel
    Chamorro, Clara
    Rios, Sandra
    Ramon Delgado, Juan
    BMC CANCER, 2014, 14
  • [35] ESR1gene promoter region methylation in free circulating DNA and its correlation with estrogen receptor protein expression in tumor tissue in breast cancer patients
    Joaquina Martínez-Galán
    Blanca Torres-Torres
    María Isabel Núñez
    Jesús López-Peñalver
    Rosario Del Moral
    José Mariano Ruiz De Almodóvar
    Salomón Menjón
    Ángel Concha
    Clara Chamorro
    Sandra Ríos
    Juan Ramón Delgado
    BMC Cancer, 14
  • [36] Epigenetic silencing of p21CIP1 in human T-lymphoblastic malignancies:: Lack of association with dense promoter-associated CpG island methylation but increased gene expression by 5-aza-2′-deoxycytidine in association with histone acetylation and release of histone deacetylase 1.
    Scott, SA
    Wei, FD
    Kimura, T
    Ichinohasama, R
    Hull, A
    Sheridan, DP
    DeCoteau, JF
    BLOOD, 2002, 100 (11) : 731A - 732A
  • [37] Perylene derivatives induce G-quadruplex formation of the proximal promoter region of the human VEGF gene and down-regulate its expression in A549 lung cancer cells
    Tuntiwechapikul, Wirote
    Joonlasak, Khajohn
    Tam-Chang, Suk-Wah
    Lee, T. Randall
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2010, 239
  • [38] Promoter CpG island hypermethylation- and H3K9me3 and H3K27me3-mediated epigenetic silencing targets the deleted in colon cancer (DCC) gene in colorectal carcinogenesis without affecting neighboring genes on chromosomal region 18q21
    Derks, Sarah
    Bosch, Linda J. W.
    Niessen, Hanneke E. C.
    Moerkerk, Peter T. M.
    van den Bosch, Sandra M.
    Carvalho, Beatriz
    Mongera, Sandra
    Voncken, J. Willem
    Meijer, Gerrit A.
    de Bruine, Adriaan P.
    Herman, James G.
    van Engeland, Manon
    CARCINOGENESIS, 2009, 30 (06) : 1041 - 1048
1234