Activation of innate immune antiviral responses by Nod2

被引：0
|
作者：
Ahmed Sabbah
Te Hung Chang
Rosalinda Harnack
Victoria Frohlich
Kaoru Tominaga
Peter H Dube
Yan Xiang
Santanu Bose
机构：
[1] The University of Texas Health Science Center at San Antonio,Department of Microbiology and Immunology
[2] The University of Texas Health Science Center at San Antonio,Department of Cellular and Structural Biology
[3] Sam and Ann Barshop Institute for Longevity and Aging Studies,undefined
[4] The University of Texas Health Science Center at San Antonio,undefined
来源：
Nature Immunology | 2009年 / 10卷
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摘要：
The intracellular 'biosensor' Nod2 responds to bacterial peptidoglycan by inducing activation of the transcription factor NF-κB. Bose and colleagues now find that Nod2 can also function as a cytoplasmic viral pattern-recognition receptor.
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页码：1073 / 1080
页数：7
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