Activation of innate immune antiviral responses by Nod2

被引:0
|
作者
Ahmed Sabbah
Te Hung Chang
Rosalinda Harnack
Victoria Frohlich
Kaoru Tominaga
Peter H Dube
Yan Xiang
Santanu Bose
机构
[1] The University of Texas Health Science Center at San Antonio,Department of Microbiology and Immunology
[2] The University of Texas Health Science Center at San Antonio,Department of Cellular and Structural Biology
[3] Sam and Ann Barshop Institute for Longevity and Aging Studies,undefined
[4] The University of Texas Health Science Center at San Antonio,undefined
来源
Nature Immunology | 2009年 / 10卷
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学科分类号
摘要
The intracellular 'biosensor' Nod2 responds to bacterial peptidoglycan by inducing activation of the transcription factor NF-κB. Bose and colleagues now find that Nod2 can also function as a cytoplasmic viral pattern-recognition receptor.
引用
收藏
页码:1073 / 1080
页数:7
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