Foreign DNA capture during CRISPR–Cas adaptive immunity

被引：0
|
作者：
James K. Nuñez
Lucas B. Harrington
Philip J. Kranzusch
Alan N. Engelman
Jennifer A. Doudna
机构：
[1] University of California,Department of Molecular and Cell Biology
[2] Berkeley,Department of Cancer Immunology and Virology
[3] Howard Hughes Medical Institute,Department of Medicine
[4] University of California,Department of Chemistry
[5] Berkeley,Physical Biosciences Division
[6] Dana-Farber Cancer Institute,undefined
[7] Harvard Medical School,undefined
[8] University of California,undefined
[9] Berkeley,undefined
[10] Lawrence Berkeley National Laboratory,undefined
[11] Innovative Genomics Initiative,undefined
[12] University of California,undefined
[13] Berkeley,undefined
[14] Center for RNA Systems Biology,undefined
[15] University of California,undefined
[16] Berkeley,undefined
来源：
Nature | 2015年 / 527卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
The structure of the Cas1–Cas2 complex bound to a protospacer sequence illustrates how foreign DNA is captured and measured by bacterial proteins in preparation for integration into CRISPR loci.
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页码：535 / 538
页数：3
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