Efficient synthesis of 2,3,4-trisubstituted furans from the reaction of activated acetylenes with ethyl bromopyruvate in the presence of enaminones

被引：0
|
作者：
Issa Yavari
Zinatossadat Hossaini
Maryam Sabbaghan
机构：
[1] Tarbiat Modares University,Chemistry Department
来源：
Monatshefte für Chemie - Chemical Monthly | 2008年 / 139卷
关键词：
Ethyl bromopyruvate; Activated acetylenes; Trisubstituted furans; Enaminone.;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The reaction of dialkyl acetylenedicarboxylates or diaroylacetylenes with ethyl bromopyruvate in the presence of enaminones led to 2-ethyl 3,4-dialkyl 4-bromo-4,5-dihydro-2,3,4-furantricarboxylates or ethyl 3,4-diaroyl-4-bromo-4,5-dihydro-2-furancarboxylate in excellent yields. These compounds are quantitatively converted to the corresponding 2,3,4-trisubstituted furans by 4-dimethylaminopyridine.
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页码：945 / 948
页数：3
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