Epigenetic clocks for gestational age: statistical and study design considerations

被引：0
|
作者：
Andrew J. Simpkin
Matthew Suderman
Laura D. Howe
机构：
[1] University of Bristol,MRC Integrative Epidemiology Unit at the University of Bristol, Population Health Sciences, Bristol Medical School
来源：
Clinical Epigenetics | 2017年 / 9卷
关键词：
Prediction; DNA methylation; Gestational age at delivery; Epigenetic clock;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the prediction of phenotypes from methylation data.
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