Evaluation of a Targeted Prodrug Strategy to Enhance Oral Absorption of Poorly Water-Soluble Compounds

被引:0
|
作者
O. Helen Chan
Heidi L. Schmid
Linda A. Stilgenbauer
William Howson
David C. Horwell
Barbra H. Stewart
机构
[1] Parke-Davis Pharmaceutical Research,Pharmacokinetics and Drug Metabolism Department
[2] Division of Warner-Lambert Company,Chemistry Department
[3] Parke-Davis Neuroscience Research Centre,undefined
[4] Addenbrooke's Hospital Site,undefined
来源
Pharmaceutical Research | 1998年 / 15卷
关键词
absorption; bioavailability; neurokinin; solubility; tachykinin; targeted prodrug;
D O I
暂无
中图分类号
学科分类号
摘要
Purpose. The purpose of this research was to examine a targeted prodrug strategy to increase the absorption of a poorly water-soluble lipophilic compound.
引用
收藏
页码:1012 / 1018
页数:6
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