HiTIMED: hierarchical tumor immune microenvironment epigenetic deconvolution for accurate cell type resolution in the tumor microenvironment using tumor-type-specific DNA methylation data

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作者
Ze Zhang
John K. Wiencke
Karl T. Kelsey
Devin C. Koestler
Brock C. Christensen
Lucas A. Salas
机构
[1] Dartmouth College,Department of Epidemiology, Geisel School of Medicine
[2] University of California San Francisco,Department of Neurological Surgery
[3] University of California San Francisco,Institute for Human Genetics
[4] Brown University,Departments of Epidemiology and Pathology and Laboratory Medicine
[5] University of Kansas,Department of Biostatistics & Data Science, Medical Center
[6] Dartmouth College,Department of Molecular and Systems Biology, Geisel School of Medicine
[7] Dartmouth College,Department of Community and Family Medicine, Geisel School of Medicine
关键词
DNA methylation; Deconvolution; Tumor microenvironment; Epigenetics; Cancer; Immune microenvironment; Tumor angiogenesis;
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