A Comparison of Drug Transport in Pulmonary Absorption Models: Isolated Perfused rat Lungs, Respiratory Epithelial Cell Lines and Primary Cell Culture

被引：0
|
作者：
Cynthia Bosquillon
Michaela Madlova
Nilesh Patel
Nicola Clear
Ben Forbes
机构：
[1] University of Nottingham,School of Pharmacy
[2] Pharmaceutical Science Division,King′s College London
[3] Charles University in Prague,Faculty of Pharmacy
[4] University of Reading,School of Pharmacy
[5] Pfizer R&D,undefined
来源：
Pharmaceutical Research | 2017年 / 34卷
关键词：
16HBE14o-; biopharmaceutics; calu-3; inhalation; isolated perfused lungs (IPL); NHBE; permeability; pulmonary;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：2532 / 2540
页数：8
相关论文
共 50 条
  • [21] Predicting ocular drug absorption using a functional primary culture of rabbit corneal epithelial cell layers model
    Lin, JEC
    Lee, VHL
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2002, 43 : U368 - U368
  • [22] Method for Primary Epithelial Cell Culture from the Rat Choroid Plexus
    Lallai, Valeria
    Ahmed, Amina
    Fowler, Christie D.
    BIO-PROTOCOL, 2020, 10 (04):
  • [23] TRANSPORT-DEPENDENT ANOXIC CELL INJURY IN THE ISOLATED PERFUSED RAT-KIDNEY
    BREZIS, M
    ROSEN, S
    SPOKES, K
    SILVA, P
    EPSTEIN, FH
    AMERICAN JOURNAL OF PATHOLOGY, 1984, 116 (02): : 327 - 341
  • [24] Corneal cell culture models: a tool to study corneal drug absorption
    Dey, Surajit
    EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY, 2011, 7 (05) : 529 - 532
  • [25] THE ISOLATED SINOATRIAL NODE CELL IN PRIMARY CULTURE FROM THE NEWBORN RAT
    MARVIN, WJ
    CHITTICK, VL
    ROSENTHAL, JK
    SANDRA, A
    ATKINS, DL
    HERMSMEYER, K
    CIRCULATION RESEARCH, 1984, 55 (02) : 253 - 260
  • [26] Development of intestinal cell culture models for drug transport and metabolism studies
    Quaroni, A
    Hochman, J
    ADVANCED DRUG DELIVERY REVIEWS, 1996, 22 (1-2) : 3 - 52
  • [27] Primary Swine Respiratory Epithelial Cell Lines for the Efficient Isolation and Propagation of Influenza A Viruses
    Meliopoulos, Victoria
    Cherry, Sean
    Wohlgemuth, Nicholas
    Honce, Rebekah
    Barnard, Karen
    Gauger, Phillip
    Davis, Todd
    Shult, Peter
    Parrish, Colin
    Schultz-Cherry, Stacey
    JOURNAL OF VIROLOGY, 2020, 94 (24)
  • [28] CISPLATIN TRANSPORT AND TOXICITY IN ISOLATED PROXIMAL RENAL TUBULAR FRAGMENTS, RENAL PRIMARY PROXIMAL CELL-CULTURE AND ESTABLISHED CELL-LINES
    RYAN, MP
    BARRON, T
    CASEY, B
    MCGUINNESS, S
    PRATT, I
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1990, 183 (05) : 1714 - 1715
  • [29] Evaluation of drug carrier hepatotoxicity using primary cell culture models
    Kibar, Gunes
    Dutta, Subhadeep
    Rege, Kaushal
    Usta, O. Berk
    NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2023, 48
  • [30] Drug permeability in 16HBE14o-airway cell layers correlates with absorption from the isolated perfused rat lung
    Manford, F
    Tronde, A
    Jeppsson, AB
    Patel, N
    Johansson, F
    Forbes, B
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2005, 26 (05) : 414 - 420
12345