Response to Hron et al.

被引：0

作者：

Peter V. Lovell

Morgan Wirthlin

Lucia Carbone

Wesley C. Warren

Claudio V. Mello

机构：

[1] Oregon Health and Science University,Department of Behavioral Neuroscience

[2] Washington University School of Medicine,The Genome Institute

[3] West Campus,Oregon National Primate Research Center

[4] Oregon Health and Science University,undefined

来源：

Genome Biology | / 16卷 / 1期

关键词：

Gene loss; Genome assembly; Gene loss; Synteny verification;

D O I：

10.1186/s13059-015-0725-y

中图分类号：

学科分类号：

摘要：

Hron et al. provide transcriptome evidence that three (1.1 %) of the 274 genes reported by Lovell et al. as missing in birds may actually be ‘hidden’ as a result of high GC content. Although this factor may explain some gene absences from genomic assemblies, we believe it is insufficient to account for the extensive syntenic losses described in Lovell et al.

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